Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new type of virus that attacks the respiratory system and has caused the global epidemic of coronavirus disease 2019 (COVID-19). Some persons who are infected with this virus develop symptoms ranging from a typical cold to fever to more severe illnesses, such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). The development of a SARS-CoV-2 vaccine is being actively researched but will likely take more than a year to become available to the general public. As a result, numerous researchers are actively extracting the components of active chemicals in herbal plants with antiviral potentials, such as patchouli (Pogostemon cablin Benth.). Patchouli essential oil, found in this Lamiaceae plant, has a wide range of effects, including antibacterial, antifungal, antioxidant, antimutagenic, anticancer, anti-inflammatory, and aromatherapy. More than 140 chemicals have been isolated and identified from the patchouli plant, including terpenoids, phytosterols, flavonoids, organic acids, lignins, alkaloids, glycosides, alcohols, and aldehydes. Patchouli essential oil is mainly composed of sesquiterpene molecules, most of which are patchouli alcohol. Essential oils derived from herbal plant extracts have also been shown to be potent antiviral agents against various viruses. The efficacy of patchouli essential oil, as well as its potential as an antiviral agent to treat SARSCoV-2, will be investigated in this review.

Patchouli oil (Pogostemon cablin Benth.) has antioxidant and antibacterial activities that can be used as an active ingredient in cosmetic products, such as body butter. Body butter preparations have the highest oil content. Therefore, they usually have the shortest storage period because they can easily damage during the storage period. The study aimed to evaluate the physical quality of patchouli oil body butter formulation in an accelerated stability test process for seven cycles. The formula was tested for its physical stability by organoleptic test, homogeneity, pH, absorption, adhesion, and dispersibility. Preparation evaluation was carried out in each cycle and analyzed using Student's t-test. The evaluation result of body butter preparation showed no significant difference (p 0.05) in the preparation in each cycle. Therefore, it can be concluded that the body butter formulation of patchouli oil was stable during the storage period for ± six months.