Highlights Users reported poor satisfaction with the computerized provider order entry system.  Reliability and user interface design are highly important in health information technology.  The switch from computerized provider order entry towards paper based order entry was well accepted.  Even in an emergency setting, the switch is possible with no perceptible impact on patient safety.  Issues identified by a satisfaction survey eased the redeployment of computerized provider order entry. AbstractIntroduction: In January 2015, Rouen University Hospital's information system experienced serious

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BackgroundMEDLINE is the most widely used medical bibliographic database in the world. Most of its citations are in English and this can be an obstacle for some researchers to access the information the database contains. We created a multilingual query builder to facilitate access to the PubMed subset using a language other than English. The aim of our study was to assess the impact of this multilingual query builder on the quality of PubMed queries for non-native English speaking physicians and medical researchers.MethodsA randomised controlled study was conducted among French speaking general practice residents. We designed a multi-lingual query builder to facilitate information retrieval, based on available MeSH translations and providing users with both an interface and a controlled vocabulary in their own language. Participating residents were randomly allocated either the French or the English version of the query builder. They were asked to translate 12 short medical questions into MeSH queries. The main outcome was the quality of the query. Two librarians blind to the arm independently evaluated each query, using a modified published classification that differentiated eight types of errors.ResultsTwenty residents used the French version of the query builder and 22 used the English version. 492 queries were analysed. There were significantly more perfect queries in the French group vs. the English group (respectively 37.9% vs. 17.9%; p < 0.01). It took significantly more time for the members of the English group than the members of the French group to build each query, respectively 194 sec vs. 128 sec; p < 0.01.ConclusionsThis multi-lingual query builder is an effective tool to improve the quality of PubMed queries in particular for researchers whose first language is not English.

Background Infective endocarditis is rare but serious. Epidemiology is well known in standard population and surgical valve patients (Pts). The recent development of Transcatheter Aortic Valve Implantation (TAVI) raises new questions about endocarditis in this population. Purpose The aim of this study was to assess outcomes of endocarditis in TAVI Pts and to compare the results to surgical aortic valve (SV) owners and native aortic valve (NV) patients. Methods We included all patients hospitalized in our institution and presenting with endocarditis after TAVI between 2012 and 2018. We compared these patients to those discussed within the “endocarditis team” and presenting with endocarditis located on SV or on NV. Results A total of 34 TAVI Pts were included and compared to a population of 45 SV and 68 NV Pts. TAVI Pts were older (83.1±1.1 yrs, vs 73.3±1.7 and 66.0±1.7, respectively; p<0.001) and had a higher Charlson score (6.2±0.4, vs 5.6±0.4 and 4.1±0.3; p<0.001). TAVI Pts underwent more frequently invasive procedures during the 6 months prior to the diagnosis of endocarditis (38.2%, vs 11.4 and 8.8%; p<0.001). They had less incidence of a new valvular murmur (0%, vs 28.9 and 33.8%; p=0.001) and less heart failure symptoms (26.5%, vs 28.9 and 33.8%; p=0.007). Clinical complications were similar between the 3 groups and mortality was high and comparable at 1 year (29.2%, vs 36.4 and 29.7% p=0.730). However, TAVI Pts were more frequently re-hospitalized (41.2% vs 26.7% and 16.2%, p=0.02) and were treated less invasively (surgery or pacemaker extraction in 14.7% vs 35.6% and 42.6%, p=0.019). Only one TAVI Pt needed surgical aortic valve replacement. Conclusion Despite more frequent comorbidities, TAVI patients affected by infective endocarditis have the same mortality during the first year after diagnosis compared to SV and NV patients but are more often rehospitalized.