Purpose: In this study, mixed extracts of Prunus persica L., BATSCH, Nelumbo nucifera, Hibiscus mutabilis L., Agastache rugosa, and Wolfiporia extensa (PNHAW), which are effective in improving skin wrinkles, was prepared. The purpose of this study is to evaluate the cosmetic functionality of this extracts through a mouse animal model.Methods: In this study, skin wrinkle width evaluation, skin moisture content, erythema amount, melanin content measurement, matrix metalloproteinase-1 (MMP-1) gene expression level in skin tissue, and safety evaluation were performed to evaluate the wrinkle improvement cosmetic function of the experimental sample.Results: As a result of this study, the experimental sample PNHAW-4 showed the best efficacy. As a result of evaluating the skin wrinkle width, the experimental group showed 19.3% less than the control group, and the skin moisture content, erythema amount, and melanin content showed superior efficacy compared to the control group. In particular, the amount of erythema of PNHAW-4 (224.5) was inhibited by 43.2% compared to the control group (395.7), and melanin was decreased by 45.9% compared to the control group. In addition, PNHAW-4 inhibited the increase in MMP-1 activity by 38% compared to the control group. As a result of the experiment, the experimental sample showed an excellent skin wrinkle improvement effect.Conclusion: The results of this study suggest that the mask pack prepared from the experimental sample has an excellent collagen production promoting effect and can be applied as a safe natural wrinkle-improving cosmetic material that does not cause skin irritation.

Since the main symptoms of COVID-19 involve the respiratory system, the infection rate of this disease is predicted to be higher in patients with other respiratory conditions such as allergic rhinitis. In such a situation, it will be meaningful to conduct research on an allergy treatment that has fewer side effects and can effectively reduce allergy symptoms. Here, we prepared experimental samples under various fermentation conditions with mixed extracts of six medicinal plants. To examine the anti-allergic efficacy of these samples, an egg albumin-induced allergic rhinitis animal model experiment, a serum histamine and IgE experiment, and a COX and LO inhibitory activity experiment were conducted. As a result of animal experiments, OVA+SP-4 showed superior efficacy compared to OVA+SP-1 in nasal rubbing and sneezing experiments and had anti-allergic efficacy similar to that of OVA-cetirizine. The serum histamine concentration of OVA+SP-4 was also 1.3 times higher than that of the OVA+cetirizine group, showing a high histamine reduction ability, and IgE showed the same trend. An analysis of COX inhibitory efficacy also confirmed that COX-1 and COX-2 inhibitory efficacy is high, and the longer the fermentation time, the higher the antiallergic efficacy. The composition proposed by this study is expected to have a significant effect on sustainable allergy prevention and treatment in the future by applying it to human patients.

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Purpose: The purpose of this study is to examine the brand equity factors for bio cosmetics and to examine how brand equity for bio cosmetics affects brand loyalty and word of mouth intention through empirical analysis.Methods: Adults in their 20s or older living in the Seoul metropolitan area who had experience in using bio cosmetics were used as the sample group. It was conducted for 2 weeks from the 2nd week to the 3rd week of March 2022, and only 232 valid data were used for the final analysis, excluding insincere responses.Results: First, it was found that brand trust and brand image, which are brand equity of bio cosmetics, had a significant effect on brand loyalty. Second, brand loyalty of bio cosmetics was found to have a significant effect on word of mouth intention. Third, brand image and brand trust, which are brand equity of bio cosmetics, were found to have a significant effect on word of mouth intention. Fourth, the partial mediating effect of brand loyalty on the relationship between brand equity (brand image, brand reliability) and word of mouth intentions of bio cosmetics was confirmed.Conclusion: This study is meaningful in that it empirically examines the relationship between brand equity and word of mouth intentions for bio cosmetics and examines the mediating effect of brand loyalty. It will have great implications for the bio-cosmetics industry preparing for the post-corona era.