From a young age, we are told that being “in sync” is a good thing! From being in sync with the music as we dance to being in sync with teammates on the field, synchronization is celebrated. However, too little or too much synchronization can be bad. In the brain, synchronization allows important information to be sent back and forth between neurons, so that we can make decisions and function in our daily lives. Mathematics can help researchers and doctors understand patterns of abnormal synchronization in the brain and help them to diagnose and potentially treat the symptoms of brain disorders. In this article, we will dive into how mathematics is used to explore and understand the brain—one of our body’s most important organs.