We discuss a case of intratracheal ectopic thyroid tissue (Err) that was retrieved fro m the fi les of the Otorhinolaryngic-Head and Neck Pathology Registry at theArmed. Forces Institute of Pathology. The patient was a 54-yearold man who had a history of pap illary thyroid carcinoma, which had been treated with a subtotal thyroidectomy. During routinef ollow-up 4 years later, the pati ent 's primary care physician detected an elevated thyroglobulin level. Further ref errals and evaluations revealed that the patient had intratracheal Err. The patient refused to undergo surgical excis ion and remains without evidence ofrecurrent carcinoma. In a MEDLINE literature review, we f ound only 13 other well-documented cases of intratracheal Errsince 1966; in all but two cases, patients had benign disease. Once the possibility of thyroid carcinoma has been eliminated by histologic examination, intratra cheal Err can be managed by complete surgical excision with the prospect of an exce llent long-term clinical outcome.
Adjuvant cryotherapy appears to alter glottis-specific wound healing, leading to decreased and more organized collagen formation and decreased keratinization with a resultant improvement in glottic function, when compared with CO2 laser surgery alone, in an acute canine injury model. Studies in humans are ongoing to further evaluate the clinical potential of cryotherapy on glottic wound healing.
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