Selected patients with stage III/IV HCC can be downstaged to Milan criteria with TACE. Importantly, patients who are successfully downstaged and transplanted have excellent midterm disease-free and overall survival, similar to stage II HCC.
This paper focuses on what happens when accountability regimes, represented in calculative planning processes, migrate onto situated, sociomaterial practices. Specifically, the article investigates what happens when the practices of results-based accountability (RBA) are translated into the social justice practices of locally-based community organizations. Based on the tenets of contemporary practice theory and a threeyear participatory action research project with community organizations in Australia, the study illustrates that performance measurement and accountability frameworks such as RBA are not technologies that peer and measure innocently and disinterestedly from a distance. Rather, RBA, as a bundle of materialdiscursive practices, is part of the performance measuring apparatus creating differences that include some things and exclude others. We articulate some of the organizing practices of social justice in a locally-based community organization, follow their translation into RBA planning practices and then return to analyse the introduction of RBA practices into the daily work of an organization. In this way, we demonstrate how situated and ongoing practices begin to unravel through intra-action with RBA boundary-making practices and its redrawn relations of accountability. project with community organizations in Australia, the study illustrates that performance measurement and accountability frameworks such as RBA are not technologies that peer and measure innocently and disinterestedly from a distance. Rather, RBA, as a bundle of material-discursive practices, is part of the performance measuring apparatus intra-acting and iteratively reconfiguring that which is included and excluded from mattering, productive of and part of what materialises. We articulate some of the organizing practices of social justice in a locally-based community organization, follow their translation into RBA planning practices and then return to analyse the introduction of RBA practices into the daily work of an organization. In this way, we demonstrate how situated and ongoing practices begin to unravel through intra-action with RBA boundary-making practices. The paper contributes to current organizational research by contesting overly simplistic, representational approaches to organizing that seek to predetermine outcomes and thereby overlook the situated and emergent character of practice.
Variceal bleeding is one of the major complications of portal hypertension. Gastric variceal bleeding is less common than esophageal variceal bleeding; however, it is associated with a high morbidity and mortality rate and its management is largely uncharted due to a relatively less-established literature. In the West (United States and Europe), the primary school of management is to decompress the portal circulation utilizing the transjugular intrahepatic portosystemic shunt (TIPS). In the East (Japan and South Korea), the primary school of management is to address the gastric varices (GVs) specifically by sclerosing them utilizing the balloon-occluded retrograde transvenous obliteration (BRTO) procedure. The concept (1970s), evolution, and development (1980s-1990s) of both procedures run parallel to one another; neither is newer than the other is. The difference is that one was adopted mostly by the East (BRTO), while the other has been adopted mostly by the West (TIPS). TIPS is effective in emergently controlling bleeding for GVs even though the commonly referenced studies about managing GVs with TIPS are studies with TIPS created by bare stents. However, the results have improved with the use of stent grafts for creating TIPS. Nevertheless, TIPS cannot be tolerated by patients with poor hepatic reserve. BRTO is equally effective in controlling bleeding GVs as well as significantly reducing the GV rebleed rate. But the resultant diversion of blood flow into the portal circulation, and in turn the liver, increases the risk of developing esophageal varices and ectopic varices with their potential to bleed. Unlike TIPS, the blood diversion that occurs after BRTO improves, if not preserves, hepatic function for 6-9 months post-BRTO. The authors discuss the detailed results and critique the literature, which has evaluated and remarked on both procedures. Future research prospects and speculation as to the ideal patients for each procedure are discussed.
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