Objective-To determine the acceptability and feasibility of screening for carriers of cystic fibrosis in a primary care setting.Design-Follow up study over 15 months of patients offered carrier testing by mouthwash.Setting
The FHQ identified most informants with genetic risks that are appropriately addressed in primary care-those with a family history of premature coronary heart disease, those warranting specialist referral, and those who might appropriately be offered carrier testing. However, it was less effective in identifying those with a possible Mendelian disorder for whom more information was required.
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