The process of facilitating the uptake of evidence, for example, scientific research findings, into the policymaking process is multifaceted and thus complex. It is therefore important for scientists to understand this process in order to influence it more effectively. Similarly, policymakers need to understand the complexities of the scientific process to improve their interaction with the scientific sphere. This literature review addresses those factors that influence the uptake of scientific evidence into policymaking, the barriers to using science in policymaking, as well as recommendations for improved science-policymaking interaction. A visual diagram of the gears of a car is used to convey the message of the complexities around the engagement between science and policymaking. It is concluded that the issue of evidence-based policymaking remains unresolved and questions for future research on the science-policy interface are raised.http://www.sajs.co.za

We have studied 80 healthy children, aged 2-14 yr, undergoing adenotonsillectomy in a double-blind, randomized design. Tracheal intubation facilitated by either suxamethonium 1.5 mg kg-1 or alfentanil 15 micrograms kg-1 was compared after induction of anaesthesia with propofol 3-4 mg kg-1. The quality of tracheal intubation was graded according to the ease of laryngoscopy, position of the vocal cords, coughing, jaw relaxation and movement of limbs. There were no significant differences in the overall assessment of intubating conditions between the two groups, and all children underwent successful tracheal intubation. Fewer patients coughed (P < 0.014) and limb movement was less common (P < 0.007) after tracheal intubation facilitated by suxamethonium. Alfentanil attenuated the haemodynamic responses to tracheal intubation.

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The primary aquifer at Atlantis (Western Cape, South Africa) is ideally suited for water supply and the indirect recycling of urban stormwater runoff and treated domestic wastewater for potable purposes. The relatively thin, sloping aquifer requires careful management of the artificial recharge and abstraction for balancing water levels. Water quality management is a further key issue at Atlantis for ensuring the highest quality potable water. Groundwater quality varies from point to point in the aquifer, while urban runoff and wastewater qualities vary greatly. The layout of the town allows for the separation of stormwater from the residential and industrial areas as well as separate treatment of domestic and industrial wastewater. This permits safe artificial recharge of the various water quality portions at different points in the aquifer, either for recycling or for preventing seawater intrusion. All of the management actions are dependent on detailed data collection and this paper describes the various parts of the system, describes the data collection activities, and provides results of the monitoring and aquifer responses over the past four decades. Challenges related to iron fouling of production boreholes are also described. The presence of emerging contaminants was studied in 2008 but requires follow-up research for establishing the extent of any possible threat to water recycling. In order to address the shortcomings of the system a risk management plan based on the Hazard Analysis and Critical Control Points approach was developed. Lessons learnt from the Atlantis experience can be transferred to other potential sites for establishment of similar systems in arid and semi-arid areas of South Africa and the African continent.