Novel coronavirus disease (COVID-19) was declared a global pandemic on March 1, 2020. Neurological manifestations are now being reported worldwide, including emergent presentation with acute neurological changes as well as a comorbidity in hospitalized patients. There is limited knowledge on the neurologic manifestations of COVID-19 at present, with a wide array of neurological complications reported, ranging from ischemic stroke to acute demyelination and encephalitis. We report five cases of COVID-19 presenting to the ER with acute neurological symptoms, over the course of 1 month. This includes two cases of ischemic stroke, one with large-vessel occlusion and one with embolic infarcts. The remainders of the cases include acute tumefactive demyelination, isolated cytotoxic edema of the corpus callosum with subarachnoid hemorrhage, and posterior reversible encephalopathy syndrome (PRES).

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he international symposium "Precincts, people and places -forging new partnerships" was organised by the University of Queensland (UQ) and the Pharmacy Australia Centre of Excellence (PACE) precinct initiative.The PACE precinct is a 1.7 hectare site adjoining the Princess Alexandra Hospital (one of Australia' s largest tertiary referral hospitals) and only 10 minutes walk from the St Lucia campus of UQ. The precinct will encompass the UQ School of Pharmacy and adjacent health-related commercial developments, the Translational Research Institute and BioPharmaceuticals Australia. The UQ School of Pharmacy will open in 2010, and other developments on the site will be phased in over the next 5 years. The location of the precinct offers an opportunity to explore innovative solutions to bioscience developments around translational research, health promotion and diseases prevention and the various forms of e-health platforms.A physical location does not, itself, ensure that those working around that precinct will interact -something else is required. While the PACE precinct offers a significant opportunity for health research innovation in that it links the universities, hospitals and medical research institutes with health industry developments, it is that "something else" we wished to debate in the "Precincts, people and places" symposium.Participants in the symposium were drawn from universities, research agencies and institutes, industry, government, and health service providers, and included architects and designers. Discussion sessions and panels were interspersed with provocations from speakers from the United States, United Kingdom and India. Transcripts of these contributions, videos of special presentations, and copies of selected presentation materials will be available on the PACE website. 1 Norman Swan, well known health journalist and commentator, moderated the symposium proceedings with energy and critical probing. Presentations from those working in health "precincts" in Australia, the UK, the US and India were interspersed with small group sessions and discussion. We are grateful for the table facilitators who helped crystallise the outcomes of the discussions.The symposium tackled the role of special precincts as productive hotspots and "living laboratories" for innovation, and examined the particular importance of precincts in the health system as a springboard and case study for discussion. Four broad challenges were identified.• How do we move beyond mere collocation to multi-party engagement and deep collaboration?• How do we better promote real innovation outcomes, and mark out a place for innovative precincts within the wider innovation system? 2 • How do we shape precincts that are "fit for purpose" in the 21st century and, in particular, how do we optimise across the physical and the virtual? What, for example, can really only be achieved by a faceto-face interaction and what can be done from a "virtual" perspective?• Within the health system, could we envisage a national effort similar in ambi...

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The main focus of the London volume is on work conducted by the Department of Urban Archaeology (of which M. was a founder member) between its inception in 1973 and its demise in 1991, although the work of others is referred to where necessary. It is a synthesis bringing together information which has either not appeared elsewhere (70% of the DUA's excavations are, as yet, unpublished) or is hidden in the variety of publications in which it did appear. The main part of the book (Chapters 4-7) charts the chronological history of the Roman town. Some people may think that much which is still speculative concerning the history of Roman London has been stated as fact but M. has addressed this accusation on p. 12, where he points out that the book provides 'an (I stress an not the) interpretation of the archaeological evidence for the town's history' (the brackets and italics are M.'s own). If one can overcome any concern for mixing archaeology and history then M.'s work is of great use; it presents the non-specialist with an easily digestible account while at the same time providing much thought-provoking material to open up discussion among other archaeologists. One of the main drawbacks of this book is the complete lack of references. This could easily have been remedied by dividing the Further Reading section between chapters and then addressing certain topics. This lack of references and the amount of explanation of archaeological terms and practices label this as a book for the general reader although the specialist may be appeased by the incorporation of specific London examples to illustrate certain points. For example, Chapter 3 contains an examination of modern dating techniques but holds the interest of the specialist by showing how stratification, coins, pottery, and dendrochronology have actually been used in London. There is a similar approach in Chapter 9, where different methods of reconstruction are illustrated (literally) using examples from London. Chapter 11 ('Citizens') was written with Francis Grew and covers the evidence from inscriptions for the people who lived in Roman London. One such person was a brickmaker who wrote an inscription on the wet clay of a tile. The author of this chapter states that the brickmaker 'was clearly more or less literate and numerate' (p. 117). This may be an understatement, however, since we are told in R. G. Collingwood and R. P. Wright, The Roman Inscriptions of Britain, vol. II, fasc. 5 (Stroud, 1993), 2491.147 that this inscription is 'a rhyming couplet of accentual iambic dimeters'. Since this chapter gives us the names of some continental merchants taken from dipinti on amphorae, I would have liked to have seen some mention in this chapter of lead sealings, which once secured packages. While it is true that the majority of the London examples bear only the initials of tria nomina rather than full names, there are at least two examples which provide more information as to the name of the sealing authority. One of these names the Tertinii family (RIB 2411.304) ...