Bicuspid aortic valve (BAV) stenosis has traditionally been perceived as a contraindication to transcatheter aortic valve implantation (TAVI) due to its specific anatomical characteristics including extensive calcifications, high leaflet coaptation and frequently encountered aortic root dilation, which may result in worse procedural outcomes and higher risk of complications. Hence, BAV patients were not included in previous clinical trials. In the recent years, improved pre-procedural imaging and technological advances have gradually enabled expansion of TAVI to patients with complex anatomy, including those with BAV. Moreover, indications for TAVI are expanding to a younger group of patients with fewer comorbidities, and BAV is more prevalent in this population. Contemporary multicenter registry-based studies indicate that patients undergoing TAVI for BAV have similar outcomes as those with tricuspid aortic valve stenosis. In this article, we provide a thorough overview of the available clinical data regarding the outcomes of TAVI in BAV, from the perspective of an experienced TAVI center with over 150 TAVIs in this group of patients, performed in our institution since the year 2009. We present anatomical and clinical classifications of BAV, differences in outcomes in patients with bicuspid and tricuspid valves, as well as important topics regarding choice of an adequate valve and valve size.
ObjectivesPatients with bicuspid aortic valve (BAV) stenosis were excluded from the pivotal trials of transcatheter aortic valve implantation (TAVI). We compared the in-hospital and long-term outcomes between patients undergoing TAVI for bicuspid and tricuspid aortic valve (TAV) stenosis.MethodsWe performed a retrospective registry-based analysis on patients who underwent TAVI for BAV and TAV at five different centers between January 2009 and August 2017. The primary outcome was long-term all-cause mortality. Secondary outcomes were in-hospital mortality, procedural complications, and valve performance.ResultsOf 1,451 consecutive patients who underwent TAVI, two propensity-matched cohorts consisting of 130 patients with BAV and 390 patients with TAV were analyzed. All-cause mortality was comparable in both groups up to 10 years following TAVI (HR 1.09, 95% CI: 0.77–1.51). Device success and in-hospital mortality were comparable between the groups (96 vs. 95%, p = 0.554 and 2.3 vs. 2.1%, p = 0.863, respectively). Incidence of procedural complications was similar in both groups, with a trend toward a higher rate of stroke in patients with BAV (5 vs. 2%, p = 0.078). Incidence of moderate or severe paravalvular leak (PVL) at discharge was comparable in both groups (2 vs. 2%, p = 0.846). Among patients with BAV, all-cause mortality was similar in self-expanding and balloon-expandable prostheses (HR 1.02, 95% CI: 0.52–1.99) and lower in new-generation devices compared to old-generation valves (HR 0.27, 95% CI 0.12–0.62).ConclusionPatients who had undergone TAVI for BAV had comparable mortality to patients with TAV up to 10 years after the procedure. The device success, in-hospital mortality, procedural complications, and PVL rate were comparable between the groups. The high rate of neurological complications (5%) in patients with BAV warrants further investigation.
Introduction. Increasingly popular physician ranking websites have lately become a significant factor in choosing a physician.Aim. The aim of this study was to establish the criteria by which patients assessed doctors on PRWs and which of these criteria were the most crucial during the general assessment of the physicians.Material and methods. Selected narrative comments from two Polish PRWs: znanylekarz.pl and rankinglekarzy.pl were analysed on the basis of the following criteria: kindness and propriety, punctuality, communication with patients, condition and equipment of a doctor's office, length of the appointment, cost of the medical advice.Results. Out of 4375 eligible comments kindness and propriety was assessed most frequently (3012 comments, 68.85%), next was communication, which was evaluated in 2343 comments (53.55%). Amongst the 3012 comments with assessed kindness and propriety, 77.66% (2339 comments) were described positively. In the group of comments with positively evaluated kindness and propriety 2230 comments (95.34 %) were generally positive. Furthermore, communication with patient was assessed in 2343 comments and in 1827 cases (77.98%) the assessment was positive. 1810 comments with positively evaluated communication were generally positive (99.07%).Conclusions. There is a connection between the patients' positive assessment and physician's kindness, personal culture and communication skills; if physicians focus on the aforementioned abilities, it might lead to better physician perception, higher effectiveness of treatment and the lower number of potential law suits.
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