We perform a detailed study of the globular cluster (GC) system in the galaxy NGC 5866 based on F435W, F555W, and F625W ($B, V, and R) Hubble Space Telescope Advanced Camera for Surveys images. Adopting color, size, and shape selection criteria, the final list of GC candidates comprises 109 objects, with small estimated contamination from background galaxies, and foreground stars. The color distribution of the final GC sample has a bimodal form. Adopting color to metallicity transformations derived from the Teramo-SPoT simple stellar population model, we estimate a metallicity ½Fe/H $ À1:5 and À0.6 dex for the blue and red peaks, respectively. A similar result is found if the empirical color-metallicity relations derived from Galactic GC data are used. The two subpopulations show some of the features commonly observed in the GC system of other galaxies, like a ''blue tilt,'' higher central concentrations of the red subsystem, and larger half-light radii at larger galactocentric distances. However, we do not find evidence of a substantial difference between the average sizes of red and blue clusters. Our analysis of the GC luminosity function indicates a V-band turnover magnitude V TOM 0 ¼ 23:46 AE 0:06, or M TOM V ;0 $ À7:29 AE 0:10 mag, using the distance modulus derived from the average of surface brightness fluctuation (SBF) and the planetary nebula luminosity function (PNLF) distances. The absolute turnover magnitude obtained agrees well with calibrations from literature. The specific frequency is measured to be S N ¼ 1:4 AE 0:3, typical for galaxies of this type.

<p>A novel coronavirus (SARS-CoV-2) has been the cause of a recent pandemic of respiratory illness known as COVID-19. The lack of anti-viral drugs or vaccines to control the infection has resulted in an enormous number of seriously ill patients requiring hospitalization. In the absence of an effective vaccine, there is an urgent need for therapies which can fight COVID-19 infection. Readily available compounds in foods and plants may be one source of anti-viral compounds. Here, natural product chemicals from the Nuclei of Bioassays, Ecophysiology and Biosynthesis of Natural Products Database (NuBBE_DB) were screened against the main protease (Mpro) of SARS-CoV-2. This protease was chosen as a target due to its importance in the replication of SARS-CoV-2. Molecular docking was used to screen the natural products against Mpro to identify potential candidates. The identified candidates were further filtered using molecular dynamics simulation investigation. Nine natural compounds were identified for experimental validation, with carlinoside and quercetin 3-o-sophoroside being the top candidates. </p>

Can and will a person become an organ donor? Before such an altruistic act will occur, there is the ethic behind the action. There is an internalization of an ethic that the person agrees or disagrees with organ donation, no matter the variant. There is a large sense of agency and responsibility over the integrity of one's body. We do care what our "network" thinks about our personally held norms of living donation and sanctity of the body. I present the position that understanding of the norms of living organ donation requires an examination of the personal social "network" surrounding the potential donor. Networks rely on connection which may lead to deliberate consensus building (or a reason to conform in order to limit disharmony). But I argue, even when there is a supportive social environment supporting a particular bioethical value, there will be some level of network level engagement with others in this process (for better or for worse).

Purpose: This study hypothesizes that tax benefits encourage the use of third-party capital, and seeks to verify whether the tax benefit deriving from debts has a positive effect on Brazilian companies' capital structure. Approach/Methodology/Design: Data on 259 nonfinancial companies over the period 2008-2018 are extracted from the Standard & Poor's Capital IQ database and are analyzed through regression with dynamic data panel. The variables considered as tax benefit proxies are: marginal tax rate, kink, standardized kink and tax payment.The investigations comprise: trade off theory, pecking order theory, information asymmetry, bankruptcy costs and agency theory. Findings: A positive debt effect on capital structure, taxation as providing a systematic incentive for greater leverage, and that, Brazilian companies, despite the country's heavy tax burden, are not taken full advantage of debt tax benefits. The study offers new evidence as to the speed of adjusting the indebtedness level relating to an optimal capital structure target. Brazilian companies have ground to contract more debt and maximize their tax benefit. Practical Implications: The study will contribute positively to the understanding of influence of high tax emerging market for the government, academia, banks, industry, managers, regulators, investors and other users. Originality/value: This study innovates by using MTR, kink and standardized kink to find debt tax benefits affecting emerging market companies' capital structure.

No abstract