Cutaneous metastases are uncommon in daily practice, although very important,
since they may be the first manifestation of an undiscovered primary neoplasm or
the first indication of recurrence. Cutaneous metastases from the breast are the
most frequent in women and cutaneous metastases from the lung are the most
frequent in men. Thyroid carcinoma, despite representing the most frequent
endocrine neoplasm, is considered a rare neoplasm, corresponding to 1% of
malignant neoplasms diagnosed. Cutaneous metastases from follicular carcinoma
are rare and occur mainly in the head and neck area. We report a case of
cutaneous metastasis in a patient with follicular thyroid carcinoma and breast
carcinoma. Because of the association of these two neoplasms, the possibility of
Cowden Syndrome - multiple hamartoma syndrome - was raised, but was excluded by
genetic analysis of PTEN gene.
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