RESUMO As proteínas de fase aguda (PFA) apresentam concentrações séricas alteradas mediante processos infecciosos, ABSTRACT Acute phase proteins (APPs) are serum proteins whose concentrations change after infectious and infl ammatory disease, and cancer. The aims of this study were to evaluate changes in APPs concentration and to correlate these fi ndings with histological classifi cation and WBC in female dogs with mammary tumors. APPs were studied in 45 female dogs with mammary tumor distributed in the following groups: benign (n=13), malignant without tumor ulceration (n=24), and malignant with tumor ulceration (n=8). SDS-polyacrylamide gel (SDS-PAGE) electrophoresis was used to measure APPs concentrations (albumin, ceruloplasmin, transferrin, haptoglobinHp,

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