Three cases of secondary leukemia developing after chemotherapy and/or radiotherapy for myeloma, mycosis fungoides, and non-Hodgkin's lymphoma are reported. The first case was a 51-year-old man with IgG-A myeloma, treated with melphalan and prednisolone, who developed acute myelomonocytic leukemia 54 months after the diagnosis of myeloma. The second case was a 54-year-old woman with mycods fungoides treated with radiation, predonine, and cyclophosphamide, who developed acute megakaryoblastic leukemia 298 months after the diagnosis of mycods fungoides. The third case was a 35year-old woman with stage IV non-Hodgkin's lymphoma treated with VEMP who developed acute myelogenous leukemia 26 months after the diagnosis of malignant lymphoma. All cases showed pancytopenia and two of three cases had morphologic abnormality in several hemopoietic cell lineages In the leukemic stage. There is a possibility that second malignancies are an increasingly recognized complication in the patients treated with a large amount of chemo-radiotherapy. ACTA PATHOL. JPN. 37 : 817-830, 1987.Representative tissue from all cases was fixed in 10% neutral buffered formalin. Sections were stained with not only hematoxylin and eosin but also periodic acid-Schiff (PAS), acid phosphatase, Azan-Mallory, and reticulin.Immunohistochemical localization of anti-Factor VIII antigen was performed using the indirect PAP method described by Sternberger.Is Cytochemical stains for peroxidase, Sudan black B, chloroacetate esterase, 0-naphthyl butyrate esterase, aminopeptidase, PAS, acid phosphatase, and 8-glucuronidase were done on bone marrow and peripheral blood smears using standard techniques.Representative material was fixed in 2% glutaraldehyde, postfixed in 1% osmium tetroxide, dehydrated in a graded series of ethanol, and embedded in Epon 812. Sections were stained with uranyl acetate and lead citrate and examined with Hitachi H-800 electron microscope. 37(5): 1987 K. NEMOTO et al. 819 37(5) : 1987 K. NEMOTO e l a1 829 provoke secondary malignancy.

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SUMMARYA converter-fed adjustable-speed generator-motor for a pumped storage power plant has been developed in order to contribute to the automatic frequency control on an electric power system during pumping operations, as well as to improve the efficiency of turbines during generating operations together with stability. This system consists of a reversible pump turbine, a generator motor, cycloconverter and control units. The rotor of the generator motor, which is coupled directly with the turbine runner, normally is operated at a rotating speed which is equal to the difference between the frequency of the electric power system and that of the rotor current. In the state that a fault has occurred in the primary circuit of the generator motor, the adjustable-speed generatormotor fault current differs from that of a conventional synchronous generator motor. This paper describes the fault current analysis results for the condition when a sudden short-circuit is made on the primary side of the generator motor, and collates the results with the field test and EMTP simulation results.

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