Prevalence of endocrine sequelae in medulloblastoma survivors is high, and evolution of endocrine dysfunction can occur as late as 15 years from treatment completion; hence, long-term close monitoring of growth, puberty and gonadal function is essential.

Background: Chronic Suppurative Otitis Media is a disease of multiple aetiology and is well known for its persistence and recurrence in spite of treatment. Changes in the microbiological profile following the advent of sophisticated synthetic antibiotics and unscrupulous usage of antibiotics increase the relevance of reappraisal of the modern day organisms in CSOM and their in vitro antibiotic sensitivity pattern. Aim: To identify bacteriological profile in our geographical area in CSOM both in TTD and AAD types, their latest sensitivity trends to antibiotics. Materials & Methods: 100 Patients with more than 3 months history of ear discharge selected over a period of 18 months. All patients are enquired about the history then subjected to ENT examination. From the discharging ear, pus taken with two sterile swabs and sent for direct smear and aerobic culture and sensitivity. Results: Gram negative organisms are predominant than gram positive. Pseudomonas is the most common organism found followed by Staph. aureus. Sensitivity in gram negative bacteria were mainly to Ciprofloxacin, Gentamycin and Amikacin. The gram positive organisms were highly sensitive to Amoxycillin/Clavulanic acid, Amikacin, Gentamycin, Ciprofloxacin and Tetracycline. Conclusion: Bacterial profile in discharging ears keep changing, latest bacteriological profile with antibiotic sensitivities needed to be obtained from time to time so as to treat the patient more efficiently.

Background 50–100 babies are born per year to drug using mothers in Leeds. Local guidelines state maternal or neonatal urine toxicology (UT) should be sent if the mother is known to use illicit substances (with the mother’s verbal consent). A local audit was conducted alongside a national survey of the use of UT in drug exposed newborn infants. Methodology Survey: Representatives from all UK neonatal networks were asked about their use and local indications for UT. Audit The case notes of infants born to drug using women in 2012 were reviewed. UT results for infants during this period were obtained from biochemistry. Results Survey 32 health professionals responded in total representing 19 of the 24 UK networks. 22% sent maternal UT and 28% sent UT from the baby. Audit 49 cases were reviewed. Maternal toxicology results were documented in 2 cases. 30 infant urine samples were received by the laboratory. 25 cases had documentation of urine being sent. 19 had documented consent. UT results identified more concerning drug use than that reported in 5/19 cases. 31 cases had discharge planning documented and urine results documented in 13/31 cases. Discussion/Conclusions National practice is variable with the majority of units discontinuing testing. Locally, despite sending UT, documentation is poor and testing does not alter management. There is a need for accurate, quick and reliable testing for infants, where drug exposure is known or suspected. The use of bedside meconium testing is being piloted locally and may provide an alternative to UT.

Background: Foreign body(FB) impaction accounts for 4% of emergency endoscopies in clinical practice. Flexible endoscopy(FE) is a recommended therapeutic option because it can be performed under local anesthesia, it is cost effective and is well tolerated. Rigid endoscopy (RG) under general anesthesia is another option and is advantageous in some circumstances. The aim of the study is to compare efcacy and safety of exible and rigid esophagoscopy in esophageal foreign body removal. Methods: It is a prospective study done in E.N.T department in KIMS MEDICAL COLLEGE, Amalapuram, which includes 50 patients with impacted foreign body esophagus. Parameters like type of foreign body, location of impacted foreign body are included. The study analyzies the type of procedure the patient have undergone, the intra operative and post operative complications. Results: This prospective cohort study includes 50 patients who have undergone surgical procedure for removal of impacted foreign body. Flexible esophagoscopy is performed in 30 patients and rigid esophagoscopy is performed in 20 patients . The most frequent complications are mucosal erosion, mucosal edema, and ulceration. Conclusion: Flexible esophagoscopy and rigid esophagoscopy are equally safe and effective for removal of impacted esophageal foreign body.

No abstract