A 63-year-old male patient presented to the outpatient department of our service with an ulcerated lesion which affected AbstractMalignant tumors which affect nasal structures are uncommon. They represent about 0.2% of all cancers and are more than twice as prevalent in males. Squamous cell carcinoma is the most common type of nasal cancer. However, basal cell carcinoma, melanoma, sarcoma and inverting papilloma can involve nose and/or para-nasal sinuses too. Although rare, these pathologies are the most frequent cause for acquired defects of the nose. In this light, the need to obtain clear resection margins obliges surgeon to perform extensive nose amputations. This report describes the case of a 63 years old man affected by squamous cell carcinoma of the nose. A total nose amputation was carried out due to the extension of the tumor. Nasal reconstruction was performed with an implant-retained prosthesis. Three dental implants were used for anchoring the nasal prostheses. This technology is safe and it ensures optimum esthetic results.

Bisphosphonates represent type of medication used for treating numerous pathologies. In fact, more and more clinicians utilize bisphosphonates for dealing oncological diseases, rheumatic pathologies and severe osteoporosis. Despite its benefits, various undesirable side effects have also been associated with the use of these drugs. For instance, patients who receive bisphosphonates present a greater risk of suffering osteonecrosis of jaw. Indeed, the possibility of experiencing this complication is around 0,812% when bisphosphonates are administered intravenously. In contrast, the risk is about 0,01% with oral administration. However, when a tooth extraction is carried out the risk rises to 0,34%. This report presents the case of a 66 years old woman who suffered a bilateral jaw fracture after prolonged treatment with bisphosphonates. Interestingly, no invasive dental procedures were referred by patient. The main aim of this paper is to focus the attention on the serious complications that this treatment may show in the long term. ResumenLos bifosfonatos son fármacos ampliamente utilizados en el tratamiento de numerosas enfermedades. Diferentes profesionales utilizan los bifosfonatos para tratar complicaciones de patologías oncológicas, osteoporosis y patologías reumatológicas. Sin embargo, a pesar de los efectos benéficos, existen efectos secundarios consecuente al utilizo de este tipo de medicamento. Por ejemplo, la osteonecrosis maxilar es más frecuente en pacientes tratados con bifosfonatos. En este sentido, la posibilidad de desarrollar osteonecrosis maxilar es del 0,812% cuando la medicación es administrada por vía intravenosa y del 0,01% en caso de administración oral. Además, cuando se realiza una extracción dental el riesgo incrementa de un 0,34%. Este artículo presenta el caso de una paciente de 66 años que sufrió una fractura bilateral y espontanea de la mandíbula tras el utilizo de bifosfonatos durante un largo periodo de tiempo. Es importante enfatizar que, en este caso, el paciente no había sido sometido a intervenciones de cirugía oral en los meses previos. El principal objetivo de este estudio es focalizar la atención sobre las posibles complicaciones provocadas por este medicamento.