Climate change is generating severe changes in the physical behavior of soils (i.e., soil structure, mechanical resistance, and water conductivity), causing negative impacts on different agricultural systems and, therefore, threatening food security. To cope with this situation, hydrogels based on biopolymers have been proposed to modify the mechanical and hydraulic behavior of complex porous materials such as soils, yet most of them are nonsoluble, making their application at field level laborious. In this study, we investigated the effect of a water‐soluble hydrogel based on bacterial alginate on the mechanical and hydraulic behavior of coarse quartz sand. The results from unconfined uniaxial compression test showed that the strength of the sand treated with hydrogel increased by 94.5%, whereas hydraulic conductivity decreased 33%. Interestingly, we observed that bacterial alginate and hydrogel shifted the mechanics of the fluid phase toward a Darcy regime. The aggregate stability tests showed that coarse quartz sand treated with hydrogel displays larger mean weight diameter, reaching 1.5 mm compared with 0.12 mm of the control (i.e., coarse quartz sand). Finally, transmission light microscopy imaging of the hydrogel treatment revealed a new three‐dimensional matrix between the quartz sand particles, changing the microaggregates and macroaggregates and providing a modified structure of the sand material. Our findings suggest that the use of the water‐soluble hydrogel improves the mechanical and hydraulic behavior of coarse quartz sand, allowing better soil conservation against climate change‐related phenomena, and is also potentially applicable in agricultural systems facing water scarcity.
IntroductionWomen with gestational diabetes mellitus (GDM) have a higher risk of developing type 2 diabetes mellitus compared with women who never had GDM. Consequently, the question of structured aftercare for GDM has emerged. In all probability, many women do not receive care according to the guidelines. In particular, the process and interaction between obstetrical, diabetic, gynaecological, paediatric and general practitioner care lacks clear definitions. Thus, our first goal is to analyse the current aftercare situation for women with GDM in Germany, for example, the participation rate in aftercare diabetes screening, as well as reasons and attitudes stated by healthcare providers to offer these services and by patients to participate (or not). Second, we want to develop an appropriate, effective and patient-centred care model.Methods and analysisThis is a population-based mixed methods study using both quantitative and qualitative research approaches. In various working packages, we evaluate data of the GestDiab register, of the Association of Statutory Health Insurance Physicians of North Rhine and the participating insurance companies (AOK Rheinland/Hamburg, BARMER, DAK Gesundheit, IKK classic, pronova BKK). In addition, quantitative (postal surveys) and qualitative (interviews) surveys will be conducted with randomly selected healthcare providers (diabetologists, gynaecologists, paediatricians and midwives) and affected women, to be subsequently analysed. All results will then be jointly examined and evaluated.Ethics and disseminationThe study was approved by the ethics committee of the Faculty of Medicine, Heinrich-Heine-University Düsseldorf (Ethics Committee No.: 2019-738). Participants of the postal surveys and interviews will be informed in detail about the study and the use of data as well as the underlying data protection regulations before voluntarily participating. The study results will be disseminated through peer-reviewed journals, conferences and public information.Trial registration numberDRKS00020283.
circa 8000 deaths in the influenza season 2017/2018 (5).Nevertheless, the rate of vaccination of at-risk patients against influenza in Germany has decreased sharply in recent years. According to an analysis of billing data from the German Association of Statutory Health Insurance Physicians (ASHIP), the national average vaccination rate for persons over 60 was 49% in the season 2006/2007, but only 34.8% in 2016/2017 (6, 7). The situation is similar for the chronically ill, for whom the vaccination rate decreased from 46.2% in the season 2010/2011 to 40.4% in 2013/2014 (8, 9).
Aim
There is little evidence of the impact of diabetes risk scores on individual diabetes risk factors, motivation for behaviour changes and mental health. The aim of this study was to investigate the effect of applying a noninvasive diabetes risk score in primary care as component of routine health checks on physical activity and secondary outcomes.
Methods
Cluster randomised trial, in which primary care physicians (PCPs), randomised (1:1) by minimisation, enrolled participants with statutory health insurance without known diabetes, ≥ 35 years of age with a body mass index ≥ 27.0 kg/m2. The German Diabetes Risk Score was applied as add-on to the standard routine health check, conducted in the controls. Primary outcome was the difference in participants’ physical activity (International Physical Activity Questionnaire) after 12 months. Secondary outcomes included body mass index, perceived health, anxiety, depression, and motivation for lifestyle change. Analysis was by intention-to-treat principle using mixed models.
Results
36 PCPs were randomised; remaining 30 PCPs (intervention: n = 16; control: n = 14) recruited 315 participants (intervention: n = 153; controls: n = 162). A slight increase in physical activity was observed in the intervention group with an adjusted mean change of 388 (95% confidence interval: − 235; 1011) metabolic equivalents minutes per week. There were no relevant changes in secondary outcomes.
Conclusions
The application of a noninvasive diabetes risk score alone is not effective in promoting physical activity in primary care.
Clinical Trial Registration: ClinicalTrials.gov (NCT03234322, registration date: July 31, 2017).
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