No abstract

Eight million people worldwide die of cancer every year. Professionals expect that their number will grow to 12 million per year by 2030. Oral cancer is currently the sixth most common carcinoma worldwide and squamous-cell carcinoma accounts for more than 90 % of all cases. Treatment choices increase with advances in medicine but at the same time complications during and after cancer therapy become more frequent. The aim of this paper is to describe the possible side effects of oral cancer treatment on the oral cavity (xerostomia, mucositis, ulcerations, radiation caries, osteoradionecrosis, secondary infections) and the ways they can be avoided and treated.

No abstract

Extensive healthcare experience in Germany has led to the establishment of medical protocols that could be borrowed for use in Bulgaria. The purpose of these protocols is to facilitate the diagnosis and treatment process regardless of the medical practitioner's experience in terms of duration, speciality, and field of expertise. The German standard in developing protocols for use in the field of oral medicine could be applied in Bulgaria.

Oral cancer is currently the sixth most common carcinoma worldwide and squamous-cell carcinoma accounts for more than 90 % of all cases. The earliest diagnosis of squamous-cell carcinoma, the better the outcome of the treatment and the prognosis. The choice of treatment depends on tumour stage. Most early squamous-cell carcinoma cases are amenable to surgical curative treatment while advanced cases commonly receive combined palliative therapy. Despite recent advance in medicine, survival rates in these patients are rarely higher than 5 years and prognosis remains poor. Our aim in this paper is to present the latest treatment options for oral squamous cell carcinoma emphasizing the monoclonal antibody therapy, oncolytic virotherapy and immunotherapy with IL2.