Phosphorylation of the nucleosides adenosine and uridine by the simple mixing and mild heating of aqueous solutions of the organic compounds with synthetic analogs of the meteoritic mineral schreibersite, (Fe,Ni)3P under slightly basic conditions (pH ~9) is reported. These results suggest a potential role for meteoritic phosphorus in the origin and development of early life.

NADH electrocatalysts have been an area of study for over 3 decades. Polyazines have been popular electrocatalysts of choice for NADH oxidation for both sensors and biofuel cell applications. However, little is known about the structure and function relationship between these polyazines and their ability for NADH oxidation. In this paper, we utilize XPS, SEM, and NMR to evaluate the structure of polyazines and relate that to their electrochemical properties.

Water at elevated temperatures (WET) can act simultaneously as reactant, solvent, and catalyst in reaction processes.

Supplemental Information S1. Materials Glycine (≥98.5%), 13 C 2-Glycine (99 atom % 13 C), paraformaldehyde (powder, 95%), 13 C-formaldehyde (20 wt. % in H2O, 99 atom % 13 C), L-serine, sarcosine, sodium hydroxide (NaOH), and LC-MS grade water were all purchased from Sigma-Aldrich and used as is. Reactions of Glycine and Formaldehyde Glycine (unlabeled and 13 C 2-labeled) was dissolved in pH 6, 8 or 10 aqueous sodium phosphate buffered solution. Varying molar equivalents of formaldehyde (unlabeled and 13 C-labeled) were then added to the glycine solution. The resulting mixtures was allowed to react at RT, 50°C and 70°C for periods up to two weeks. By varying the stoichiometry, temperature and pH, the optimal reaction conditions for glyoxylate yield could be determined. 13 C NMR Analysis 13 C NMR data were obtained using a Bruker Avance II-500 spectrometer and a Bruker Avance III-400