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The study proposed an approach for synthesis‐Layered Double Hydroxide nanoparticles by the coprecipitation method in solution containing two divalent and trivalent metal salts, calcium, and aluminum. The synthesized calcium‐layered Double Hydroxide (CAL) used for intercalating an anti‐inflammatory drug with the purpose of obtaining controlling release rate, protecting of drug from decomposition and raising the poor aqueous solubility of drug. Mefenamic acid (ME) as anti inflammatory drug was intercalated into CAL from ion‐exchange route to preparation CAL/ME nanohybrids. An increase in the space of interlayer of the (002) plane from 8.06 Å in pristine CAL to 34.51 Å in the nanohybrid confirmed successful intercalation of ME anion into CAL framework, which was ordered in a bilayer fashion with the carboxylate functional groups in the interlayer gallery of CAL. The x‐ray diffraction and FTIR study indicated that the ME was successfully intercalated into interlayer space of CAL. The chemical composition of samples was evaluated by ICP‐OES and energy‐dispersive spectrum analysis. TG analysis confirmed that the thermal stability of intercalated ME in the form of nanohybrid was enhanced. dynamic light scattering and field emission scanning electron microscopy were determined the size of CAL particles. Finally, in vitro drug release experiments of nanohybrid at a PH of 4.8 and 7.4 showed sustained release profiles with ME anions as an anti‐inflammatory model drug.

The second cause of death in the world has been reported to be cancer, and it has been on the rise in recent years. As a result of the difficulties of cancer detection and its treatment, the survival rate of patients is unclear. The early detection of cancer is an important issue for its therapy. Cancer detection based on biomarkers may effectively enhance the early detection and subsequent treatment. Nanomaterial-based nanobiosensors for cancer biomarkers are excellent tools for the molecular detection and diagnosis of disease. This review reports the latest advancement and attainment in applying nanoparticles to the detection of cancer biomarkers. In this paper, the recent advances in the application of common nanomaterials like graphene, carbon nanotubes, Au, Ag, Pt, and Fe3O4 together with newly emerged nanoparticles such as quantum dots (QDs), upconversion (UCNPs), inorganics (ZnO, MoS2), and metal-organic frameworks (MOFs) for the diagnosis of biomarkers related to lung, prostate, breast, and colon cancer are highlighted. Finally, the challenges, outlook, and closing remarks are given.

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This study presents a new and rapid method for preconcentration, measurement, and removal of trace amounts of coloured wastewater using chitosan functionalized magnetic carbon nanotubes in aqueous samples. This method involves a two-phase system in which the donor phase contains an aqueous phase with bromocresol green, and the acceptor phase contains functionalized magnetic carbon nanotubes with chitosan. Experiments were carried out in two stages of extraction of bromocresol green from aqueous solution and desorption of bromocresol green using ethanol solvent. The samples were analysed by UV-Vis spectrophotometer. Extraction parameters were investigated such as the effect of organic solvent, pH of the donor and acceptor phases, extraction time, interference species, and volume of elution solvent. The isotherm of bromocresol green adsorption was fine described by the Langmuir model, and the adsorption capacity in the maximum was 28.49 mg g −1 . The preconcentration factor and limit of detection for bromocresol green were 14.3 and 7.5 μg L −1 , respectively. A linear range is observed between 0.1 and 20 mg L −1 . Finally, the chitosan functionalized magnetic carbon nanotubes (Fe 3 O 4 @MWCNT-CN) exhibited a high potential for removing the bromocresol green from aqueous samples.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.