Immature teratomas of the ovary represent less than 1% of all ovarian teratomas. They contain several tissues that derive from the three embryologic layers: ectoderm, mesoderm, and endoderm. We report the case of a 17-year-old girl who presented with an immature teratoma of the left ovary that recurred 3 months later as an inoperable malignant neuroepithelial peritoneal tumor resembling a glioblastoma. She died 3 weeks after the second explorative operation. The very aggressive course and fast lethal outcome could be explained by the patient's refusal to receive chemotherapy after the initial operation.

The possibility for war veterans to obtain the right to disability and financial compensation due to a diagnosis of PTSD might interfere with the proper diagnostic assessment and thus the treatment outcome. During the procedures for the obtention of these rights, exaggeration or simulation of symptoms are common. The quality of the diagnostic assessment of PTSD can be improved by applying evidence based standardized procedures.

Uvod:Veliki i multipli miomi su dobro poznat uzrok infertiliteta, ali nije neuobičajeno da i pored njihovog prisustva dođe do spontane trudnoće. Tretman pacijentkinja sa velikim i multiplim miomima je kontroverzan, ne samo u toku trudnoće već i prilikom porođaja. Ovakvi miomi mogu da budu uzrok značajnog morbiditeta u puerperijumu. Carski rez je najčešći način završavanja porođaja. Prikaz slučaja: Carski rez sa polimiomektomijom učinjen je u 36. nedelji gestacije, kod pacijentkinje sa velikim multiplim miomima, uz upotrebu cell savera, sa dobrim fetalnim i maternalnim ishodom. Pristup donjem segmentu uterusa je bio moguć uprkos postojanju velikih mioma. Živo novorođenče, telesne mase 2600 grama, rođeno je bez teškoća. Nakon zbrinjavanja histerotomije, učinjena je ekstrakcije najvećeg mioma (210 × 180 ×155 mm) i njegovo ležište je ušiveno u dva sloja. U toku miomektomije, korišćen je cell-saver i spasena je značajna količina krvi. Pošto je ustanovljena adekvatna hemostaza, odlučeno je da se ukloni i preostalih osam mioma, što je i učinjeno, bez otvaranja materične duplje. Zaključak: Mali je broj radova koji prikazuju intraoperativno "spasavanje krvi" kao tehniku kojom se rešava intraoperativno krvarenje u toku miomektomije, tokom carskog reza. Naš slučaj dokazuje da intraoperativno "spasavanje krvi" u kombinaciji sa velikim hirurškim iskustvom u klasičnoj miomektomiji značajno poboljšava ishod ovakvih operacija.

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INTRODUCTION. There are dilemmas and contradictions in the therapeutic approach to each stage of prostatic cancer, and particularly in the application of hormonal therapy during the disseminated stages of the disease, where the crucial dilemma is: whether to apply constant or temporary (intermittent) hormonal therapy. OBJECTIVE. The objective was to compare different hormonal procedures, to reach a conclusion about which mode of hormonal therapy or hormonal control of disseminated prostatic cancer is best, as well as about which tumour characteristics have an effect on the outcome of the treatment. METHOD. Two groups of patients with disseminated prostatic cancer were treated using two different methods. One group, of 102 patients, was treated using constant hormonal therapy, while the other group, of 80 patients, was treated with intermittent antiandrogen therapy with a total androgenic blockade (TAB). Statistical analysis was used to examine the relative therapeutic effectiveness in these two groups. RESULTS. The effectiveness of hormonal therapy depends upon the malignancy potential of the tumour, i.e., therapy is the least-effective in tumours with the highest malignancy potential, where primary hormonal resistance was recorded in 35.7% of the patients, and secondary resistance in 100% of the patients, during the follow-up period of 39.1 months. In the group that was administered intermittent antiandrogen therapy during nearly the same time period, secondary resistance was reported in 20% of the patients, while in the group covered by constant therapy, it was reported in 50% of the patients, which represented a significant difference (p<0.05). CONCLUSION. The hormonal resistance of prostatic cancer relates directly to the malignant potential of the tumour, i.e., its grade and stage of malignancy. Intermittent antiandrogen application with Thas a significant effect on the time it takes for a tumour to develop hormonal resistance. Therefore, such a procedure reduces the side-effects and treatment costs of hormonal therapy.