The risk of CD in the Saharawis is only modestly increased in first-degree relatives compared with the general population, probably because of the higher frequency of CD predisposing genes in the general population. Saharawi patients with CD receiving GFD showed poor adherence to the treatment, which could contribute to residual CD-related morbidity and mortality.

S2 New technologies, new opportunities, new interpretative challenges in molecular genetics of Cystic Fibrosis Alessandra Coiana