Solid-state fermentation may produce therapeutic compounds with higher biomass or better product characteristics than those generated by submerged fermentation. The objectives of this study were to analyze the antioxidant activities and biosafety of products obtained by white truffle (Tuber magnatum) solid-state fermentation in media with different ratios of soybean and red adlay. High levels of antioxidant components and high antioxidant activities such as DPPH radical scavenging, ferrous ion chelation, and reducing power were measured in 20 mg/mL water and ethanol extracts of the white truffle fermentation products. When the solid-state fermentation medium contained soybean and red adlay in a 1:3 ratio (S1A3), the fermentation product had more uniform antioxidant compositions and activities by principal component analysis (PCA). In addition, a 200 ppm water extract of the mycelial fermentation product was able to protect zebrafish embryos from oxidative stress induced by 5 mM hydrogen peroxide. Sprague–Dawley rats were fed the mycelial fermentation product for 90 consecutive days, revealing a no-observed-adverse-effect level (NOAEL) of 3000 mg/kg BW/day. Therefore, mycelial products obtained by white truffle solid-state fermentation can be used instead of expensive fruiting bodies as a good source of antioxidant ingredients.

Deep reactive ion etching (DRIE) process is one of the most popular fabrication techniques due to its flexibility between anisotropic and isotropic etching, and high etching selectivity. The alternating etching cycle flowing only etching gas of SF 6 and then switching to sidewall passivation cycle using only C 4 F 8 is used. However, the etching results depend on the process conditions such as gas flow rate, electrode power, pressure, temperature and cycling time. The origins of various etching rate together with its effects on the performances of lateral comb-drive sensor, in terms of electrostatic force, mechanical stiffness, stability and displacement, are discussed. The capacitance MEMS sensitivity is decided by comb structure profile, and comb top width and bottom width tolerance are important size. These fabrication tolerances are expected to affect the performances of MEMS devices, this paper using 20% etching ratio to do deep comb structure process and successful to improve the comb structure profile.