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Introduction: Primary chest wall tumours are very rare. Chondrosarcoma represents 40% of all chest wall tumours. Wide local excision with tumour free margins has been the gold standard therapy. We evaluated this therapy in relation to various prognostic factors for anticipating the recurrence of the tumour.Material and methods: 22 cases of Primary chest wall chondrosarcoma was operated upon from 2009 to 2019 with wide local excision with adequate margins. Male constituted 77.27% and females 22.73% with the tumour size ranging from 5 to 30 cm in size(median 7cm).Results: 19 patients were subjected to lateral chest wall resection. 3 cases underwent partial sternectomies. Resection was extended to lungs in 7 cases, diaphragm in 2 cases, vertebral body in 2 cases and clavicle in 2 cases. Reconstruction was done with polypropylene or titanium mesh and a muscle flap coverage. There was no perioperative mortality. Postoperative complications occurred in 13.6%(n=3). There was recurrence in 4 cases within 5 years. 5year disease free survival rate was 81.81%. Conclusions:Wide local excision with tumours free margins still remains the standard form of therapy. The reconstructive procedures have evolved largely to cover the huge defects following surgery. Post operative adjuvant therapy is guided by various prognostic factors.

BACKGROUNDAcute pancreatitis is the final result of premature pancreatic pro-enzyme activation leading to "auto digestion" of the parenchyma, thereby inducing a cascade of inflammatory response which further damages the organ. Theoretically inhibition of pancreatic secretion may prove useful in management of acute pancreatitis. There are evidences that somatostatin and octreotide apart from having inhibitory effect on pancreatic secretion also has some cytoprotective properties and that they counter the ileus and bacterial translocation in acute pancreatitis.

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