Tourism can transcend governmental boundaries by bringing people closer together through the understanding of different cultures, heritages, and beliefs. Therefore, it is potentially one of the most important vehicles for promoting peace among the peoples of the world. Although previous South Korean governments have historically proposed a variety of actions to contribute to peace on the Korean Peninsula, there has been little success. However, the Mt. Gumgang tourism development, the hallmark of the Sunshine Policy of former president of South Korea, Dae Jung Kim, is different from previous tourism initiatives as it has had more tangible and practical outcomes that have contributed to the promotion of peace on the divided Peninsula. To this end, the South Korean government has applied the insights of neofunctionalism to the Mt. Gumgang tourism development. This is an approach to integration theory from the perspective of liberalism that has been heralded in international politics. According to this approach, it is expected that the Mt. Gumgang tourism development can be used as a tool to maintain peaceful circumstances, which results in spill-over effects, enlargement of activity scopes, and a heightened level of commitment on the Korean Peninsula. The purpose of this study is to empirically test the hypothesis that the Mt. Gumgang tourism development contributes to the peace of the Korean Peninsula by employing the theory of neofunctionalism. To test this hypothesis, this study proposes a Peace Index and investigates the spill-over effects by utilizing the Mt. Gumgang tourism development as a test case. The results of this study indicate that the view that tourism contributes to peace is valid but tenuous since the impact of the Mt. Gumgang tourism development in the promotion of peace was less significant than expected. Consequently, the results of this study also indicate that neofunctionalism, which has been developed for western political systems, needs to be re-examined when applied to the unique, dynamic, and complex political circumstances on the Korean Peninsula. r

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To generate accurate next-generation sequencing (NGS) data, the amount and quality of DNA extracted is critical. We analyzed 1564 tissue samples from patients with metastatic or recurrent solid tumor submitted for NGS according to their sample size, acquisition method, organ, and fixation to propose appropriate tissue requirements.Of the 1564 tissue samples, 481 (30.8%) consisted of fresh-frozen (FF) tissue, and 1,083 (69.2%) consisted of formalin-fixed paraffin-embedded (FFPE) tissue. We obtained successful NGS results in 95.9% of cases. Out of 481 FF biopsies, 262 tissue samples were from lung, and the mean fragment size was 2.4 mm. Compared to lung, GI tract tumor fragments showed a significantly lower DNA extraction failure rate (2.1 % versus 6.1%, p = 0.04). For FFPE biopsy samples, the size of biopsy tissue was similar regardless of tumor type with a mean of 0.8 × 0.3 cm, and the mean DNA yield per one unstained slide was 114 ng. We obtained highest amount of DNA from the colorectum (2353 ng) and the lowest amount from the hepatobiliary tract (760.3 ng) likely due to a relatively smaller biopsy size, extensive hemorrhage and necrosis, and lower tumor volume. On one unstained slide from FFPE operation specimens, the mean size of the specimen was 2.0 × 1.0 cm, and the mean DNA yield per one unstained slide was 1800 ng.In conclusions, we present our experiences on tissue requirements for appropriate NGS workflow: > 1 mm2 for FF biopsy, > 5 unstained slides for FFPE biopsy, and > 1 unstained slide for FFPE operation specimens for successful test results in 95.9% of cases.