The CagA+ strain of H. pylori, can not only be a trigger, and may also have a role via chronic inflammation in the pathogenesis of CSX.

Background Coronary sow-flow phenomenon (CSFP) is defined as slow passage of the contrast injected into the coronary arteries without distal obstruction of the vessel. Methods The present study was a cross-sectional, descriptive-analytical study performed at the Seyed-al-Shohada Heart Center during 2018–2019. The eligible patients based on the inclusion and exclusion criteria were divided into the study group showing the CSFP and the control group with normal epicardial coronary arteries. Results The study included 124 patients. 67.9% of the study group and 39.4% of the control group were male patients (p-value = 0.001), and the mean patient age was 52.18 ± 12.55 and 51.77 ± 10.36 years in the study and control groups, respectively (p-value = 0.18). The study group had a significantly higher BMI than the control group (p < 0.05) and also a higher prevalence of smoking and hypertension. The variables of ALC, Hct, Plt, MPV, RDW, Cr, triglyceride, TC, and LDL, were higher in the study group. Given the echocardiographic findings, the mean E wave was significantly lower in the study group, while the control group had a significantly higher GLS (p-value = 0.01). Also, left anterior descending artery was the most common artery involved with CSFP. Conclusion The CSFP was significantly more common in men, smokers, hypertensive patients, and patients with high BMI. Moreover, these patients had significantly higher platelet count, MPV, LDL, and FBS. Some other laboratory variables were also higher in these patients. Given the echocardiographic findings, mild diastolic dysfunction and low GLS were also observed in the study group.

Background and aims Coronary Slow flow is a phenomenon known as slow contrast flow that injected into the coronary arteries, without epicardial coronary arteries obstruction. The etiology of this disease is unknown. Endothelial dysfunction, known as a major cause of Coronary Slow flow syndrome (CSF). Methods: This study was cross-sectional (descriptive-analytic), which was performed on patients admitted to Seyedoshohada Heart Center, during one year (2018-2019). Considering the inclusion and exclusion criteria, patients were divided into two groups of normal coronary arteries (NECA, as the control group) and with the Coronary slow-flow (CSF). Results: In the present study, 124 patients were studied, 67.9% in the coronary slow flow group and 39.4% in the control group were men (p=0.001). In the coronary slow flow group, the mean age of patients was 52.18 ± 12.55 years and in the control group, the mean age was 51.77 ± 10.36 years (p=0.18). Mean BMI was significantly higher in the coronary slow flow group than the control group (p <0.05). The smoking, hypertension, and mean of Lymphocyte, Hb, Hct, Plt, MPV, RDW, BUN, FBS, TG, TC, LDL was significantly higher coronary slow flow group. Also, in echocardiography, the mean E wave, E/A ratio was significantly lower in the coronary slow flow group. The GLS was also significantly lower in the control group (p=0.01). LAD was the most common type of coronaries that involved with a slow flow. Conclusion: The results of this study showed that there was a significant increase in the rate of coronary slow flow in men, smokers, high BMI, and hypertensive patients. Also, platelet count, MPV, LDL, FBS, and some laboratory variables were high in patients with CSF. Mild diastolic dysfunction and low GLS were observed in this group of patients.