We report an unusual case of valacylovir-induced nephrotoxicity. The study presents the case of a 38-year-old female patient who developed acute renal injury following treatment with a single oral dose of valacyclovir (2000 mg). Although nephrotoxicity due to rapid intravenous infusion of valacyclovir at high doses is not a rare side effect, oral single doses associated acute renal injury is an uncommon complication. Valacylovir is a commonly used antiviral agent; therefore, physicians should be aware of this rare but potentially serious adverse drug reaction.

No abstract

Objective:   There are few studies in the literature suggesting that epileptic attacks can cluster especially in winter. We aimed to confirm the most frequent month and season in which our patients with epilepsy visited the emergency room because we had similar observations in our clinical experience. Material and Methods: Patients admitted to the emergency room due to convulsive epileptic seizures between January 2017 and December 2019 were included in the study. The month of seizures was recorded. Results: In our study, epileptic seizures clustered significantly in winter. Conclusion: Although more detailed data should be collected on this subject, we think this is an indirect result of the change in vitamin D metabolism, as suggested in other studies.

No abstract

No abstract