No abstract

Objective: This retrospective study was designed to describe the morbidity, mortality rates and risk factors in adult urban population Bishkek, Kyrgyz Republic for the period 2004–2019 using data from the Stroke Registry. Methods: The data were derived from Stroke Registry between 2004 and 2019 in Bishkek through examination of records of patients admitted to hospitals and those receiving treatment at home prescribed by doctors of Registry. A retrospective epidemiological study of the long-term dynamics of the morbidity and mortality rates between 2004 and 2019 was performed. The growth (drawdown) rate was calculated using the least-squares method to align the time series. A comparative analysis of the rates was carried out by calculating the long-term average annual level of incidence by gender and age. Ethical approval was not necessary for the preparation of this article. Results: The most common type of stroke registered for the population of Bishkek was ischemic stroke (IS) (68.5%), followed by hemorrhagic stroke (HS) (21.4%) and cryptogenic stroke (10.1%). During the analyzed period of time there has been a moderate decrease in the incidence of IS (4,0%) and a notable decrease of HS (9,0%) and cryptogenic (26,9%) strokes. As for stroke mortality in long-term dynamics, we could observe an essential decrease in this indicator in all strokes (IS-13.0%, HS 13.6%, cryptogenic ones-37.7%). The most remarkable risk factor for stroke was arterial hypertension (86.5%). Cardiovascular pathology of another origin was detected in 32.7% of patients. Conclusion: Our results further help to understand what changes have been in the long-term dynamics of the incidence and mortality of stroke in Kyrgyzstan, in relation to which risk factors for stroke should be taken more action. There is a need to continue to strengthen prevention at the population level, to assess and manage the risk of cardiovascular disease in primary healthcare. Such measures will help prevent complications and support efforts to prevent relapse and disability.

Brain tumours cause considerable concern due to a high mortality and there are increasing efforts to provide adequate care. The goal of this study was to determine the incidence of brain tumours in Kyrgyz Republic. A population based study was performed. Patients from Kyrgyz Republic with incident intracranial tumours diagnosed in 2005 and 2007 (by CT, MRI or histology) were identified retrospectively using multiple sources. Differences in incidence by tumour type, age and sex were examined. Eight hundred and eighty four patients with incident brain tumours were identified (456 primary tumours and 428 secondary tumours). The commonest primary tumours were neuroepithelial tumours (53,5%), meningeal tumours (19,5%), and sellar tumours (16,5%). The crude yearly incidences of primary and secondary tumours were 30,3 and 28,3 per 100 000 respectively. About 50% of patients with secondary tumours had an underlying lung cancer. The incidence of primary and secondary tumours increased markedly with age. Meningeal tumours were more common in women. This study shows that the incidence of intracranial tumours in Kyrgyz Republic is considerably higher than previously thought. Brain tumours are a significant cause of morbidity and mortality in Kyrgyz Republic, and further research into their aetiology and treatment is urgently required.