Rotigotine improvement in the multi-domain NMSS total score was not superior to placebo. A different sensitivity of individual NMSS domains to dopaminergic therapy and a large placebo effect may have contributed to these findings.
These results demonstrated bioequivalence and indicated similar adhesiveness of the approved room temperature stable rotigotine patch with the original and cold chain patches. Potential limitations include the enrolment of healthy volunteers in the bioequivalence studies, as these individuals were likely to be younger than the general PD or RLS population.
Miriam Schmid ist Projektleiterin bei der Jugendstiftung Badenwürttemberg und dort u. a. zuständig für die Jugendstudie Baden-württemberg. wolfgang antes ist geschäftsführer der Jugendstiftung Badenwürttemberg. die Jugendstiftung Baden-württemberg entwickelt, berät, fördert und verantwortet Jugendbildungsprojekte und Programmlinien, die an der Schnittstelle zwischen außerschulischer Jugendbildung, Schule und Berufsfeld wirken.
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