No abstract

The present study demonstrated a significantly enhanced gastric emptying of the solid meal test in morbidly obese patients when compared to lean subjects. This finding is compatible with the hypothesis that rapid gastric emptying in morbidly obese subjects increases caloric intake due to a more rapid loss of satiety.

High pressure torsion offers unique conditions for the consolidation of metallic particles at room temperature owing to the high hydrostatic compressive stresses combined with the high shear strain. A Mg-Al 2 O 3 composite was produced by consolidation of machining chips of pure magnesium with 10% in volume of alumina particles. The consolidation process was investigated by optical and scanning electron microscopy and X-ray microtomography. It is shown that shear deformation concentrates along thick alumina particle layers in the initial stage of deformation. A significant fraction of the hard phase particles are pushed into the outflow in quasiconstrained HPT and a homogeneous composite is achieved after significant straining. The composite exhibits a refined microstructure, a higher hardness and improved resistance against room temperature creep compared to pure magnesium.

Hydroxyapatite and bioactive glass particles were added to pure magnesium and an AZ91 magnesium alloy and then consolidated into disc-shaped samples at room temperature using high-pressure torsion (HPT). The bioactive particles appeared well-dispersed in the metal matrix after multiple turns of HPT. Full consolidation was attained using pure magnesium, but the center of the AZ91 disc failed to fully consolidate even after 50 turns. The magnesium-hydroxyapatite composite displayed an ultimate tensile strength above 150 MPa, high cell viability, and a decreasing rate of corrosion during immersion in Hank’s solution. The composites produced with bioactive glass particles exhibited the formation of calcium phosphate after 2 h of immersion in Hank’s solution and there was rapid corrosion in these materials.

IntroduçãoAproximadamente 42 milhões de pessoas no mundo apresentavam-se infectadas pelo vírus da imunodeficiência humana (HIV)