Тяжелая черепно-мозговая травма может вести к длительному нарушению сознания с различными клиническими проявлениями, которые трудны для дифференцировки и прогнозирования развития. В работе на основе записей биопотенциалов были реконструированы и проанализированы функциональные связи мозга, активирующиеся при прослушивании тонов у 20 пациентов с нарушением сознания вследствие травмы мозга. Показано, что у пациентов с затяжным нарушением сознания возможно увеличение числа функциональных связей в лобный отделах, тогда как число «вертикальных» связей снижено. У пациентов с хроническим нарушением сознания значительно снижено число функциональных связей, причем даже в тех случаях, когда отмечается анатомическая сохранность трактов мозга. Можно полагать, что выявленные особенности функциональных связей будут способствовать более точной оценке состояния пациентов, с которыми невозможен вербальный контакт, а также прогнозу возможности восстановления сознания и подбору наиболее адекватной терапии.
Introduction. Lumbosacral radiculopathy is а leading cause of long-term disability. Taking into a consideration the duration of treatment radiculopathy, the risk of developing adverse reactions when taking analgesics, non-steroidal anti-inflammatory drugs, the physiotherapeutic method — repetitive peripheral magnetic stimulation may become a promising method of therapy.Aim of the study. Assessment of the effectiveness of the complex treatment for patients with lumbosacral radiculopathy using the course of the repetitive peripheral magnetic stimulation.Materials and methods. Forty patients with lumbosacral radiculopathy were enrolled in the open non-randomized study, were divided into 2 parallel groups. The patients of the 1st group received a course of traditional treatment and a course of the repetitive peripheral magnetic stimulation. The patients of the 2nd group were treated with the traditional treatment without the course of the stimulation. A magnetic stimulator MagPro (Magventure, Denmark) was used for repetitive peripheral magnetic stimulation.Results. A significant difference (p <0.001) was registered regarding the reduction of pain syndrome and the improvement of the functional status after treatment in both groups. 14 (70 %) patients of the first group achieved a pain visual analogue scale relief by 50 % after 10 repetitive peripheral magnetic stimulation sessions, while 6 (30 %) patients did this after 15 repetitive peripheral magnetic stimulation sessions. We did not observed a statistically significant differences (p >0.05) in pain syndrome, functional status, anxiety level at the end of follow-up between the groups.Conclusion. We did not receive the benefits of the repetitive peripheral magnetic stimulation course in comparison with a traditional treatment of a lumbosacral radiculopathy. Further placebo-controlled studies to study the effect of repetitive peripheral magnetic stimulation on pain and anxiety in patients with back pain and radiculopathy are required.
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