Two cases (a 23-year-old man and a 33 year-old-woman) with Bland-White-Garland (BWG) syndrome (an anomalous origin of the left coronary artery from the pulmonary artery) are presented. Their first symptom was survived sudden cardiac death. Both patients underwent surgical repair. One patient received an implantable defibrillator because of serious structural changes in the left ventricle and symptomatic non-sustained ventricular tachycardia; the second patient is free of therapy. During long-term follow-up (10.5 and 4.5 years, respectively), ventricular tachyarrhythmias did not recur. Both cases show good long-term prognosis in resuscitated adult patients after surgical repair for BWG syndrome regardless of the presence of structural changes.
Tumours of the mammary gland were diagnosed in one female Djungarian hamster (Phodopus sungaros) and in two of her daughters from two litters. Altogether, five tumours were diagnosed. Three of them were adenocarcinomas, one was adenoma with disseminated foci of adenocarcinoma and one was diagnosed as an atypical fibrosarcoma derived from cutaneous ganglion cell-like cells. This was a recurrent tumour in the proximity of the previously extirpated adenocarcinoma. Using specific PCR primers for conserved regions of the mouse mammary tumour virus (MMTV) no endogenous provirus DNA could be detected in DNA samples isolated from formalin-fixed paraffin embedded tissue sections.Keywords: hamsters; neoplasias; atypical fibrosarcoma; mammary gland; clinic; pathology; molecular biology Hamsters are popular pet animals with Syrian hamsters (Mesocricetus auratus) and Djungarian hamsters (Phodopus sungaros) being among the most frequently kept species. Reports on spontaneous tumours in domestic hamsters are scarce, and most are individual case reports (Kondo et al. 2008a). The incidence of tumours in these two species is quite different. In the analysis of tumours from 85 domestic hamsters 70 were Djungarian hamsters and 15 Syrian hamsters (Kondo et al. 2008a). In the integumentary system of Syrian hamsters melanomas and cutaneous lymphoma are the most frequently detected tumours, but both are low in incidence (Percy and Barthold 1993;Brown and Donnelly 2012). Tumours of the mammary gland in Syrian hamsters are rare and only a few cases have been described in the literature (e.g. Jelinek 1986a). However, in Djungarian hamsters the incidence of cutaneous neoplasias is five times greater than in Syrian hamsters and these are predominantly represented by mammary tumours, atypical fibromas and papilomas (Brown and Donnelly 2012). Kondo el al. (2009) analysed mammary tumours from 12 domestic Djungarian hamsters. Eleven were female and one was male. Histopathology revealed three subtypes: simple adenoma, tubulopapillary carcinoma, and complex carcinoma. No angioinvasion was observed. It is the aim of this contribution to describe mammary neoplasias in a female of Djungarian hamster and her two daughters. Case descriptionClinical and gross pathology. The owners of the pets in question originally intended to acquire two female Djungarian hamsters as pets. However, in the pet shop they purchased, by mistake, one male and one female. Two months later the female gave birth to four young. After weaning, three young animals (two females and one male) and the father were sold back to the pet shop and the family retained the mother and her daughter. The mother was, however, fertilized before the weaning of offspring and one month after the first parturition, bore a second litter of young comprised of two hamsters; one died shortly after birth while the other, female, survived.A tumour of the first left mammary gland was observed in the mother at the age of 15 months. At the time of extirpation its size was 2 × 1 × 1 cm
Transjugular intrahepatic portosystemic shunt is a minimally invasive endovascular procedure that has played an important role in the treatment of acute or repeated variceal bleeding or refractory ascites. The standard venous access route for this procedure is the right jugular vein. Sometimes it is better to use the left jugular vein because of lower probability of life threatening complication or technical failure. In this case reports the authors have described their experience with TIPS creation in two patients with persistent left and absent right superior vena cava and recommend using the left jugular vein as an access route in this rare anatomical variant.
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