To understand the mechanism underlying the high radio-sensitisation of living cells possessing brominated genomic DNA, X-ray photoelectron spectroscopy (XPS) using synchrotron X-rays with energies of 2000 or 2500 eV was...

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Purpose To evaluate the foveal avascular zone (FAZ) and retinal structure in familial exudative vitreoretinopathy (FEVR). Patients and Methods Eighteen eyes with stage 1 or 2 FEVR and 20 control eyes were evaluated. The central retinal thickness (CRT), foveal inner retinal thickness (IRT), surface retinal vessel density (SRVD), and deep retinal vessel density (DRVD) were measured using optical coherence tomography. The FAZ area was calculated using ImageJ software. The equivalent spherical value (SE) and axial length (AL) were measured. Results The CRT (232.5±3.086 vs 211±12.6325 μm; p =0.003) and foveal IRT (15.83±13.95 vs 0.9±4.02 μm; p =0.002) were thicker in the FEVR group than in the control group. The surface FAZ area (0.265±0.08 vs 0.364±0.09 mm 2 ; p =0.004) and the deep FAZ area (0.364±0.1 vs 0.484±0.11 mm 2 ; p =0.03) were smaller in the FEVR group than in the control group. The SRVD values did not differ among the sectors, but the DRVD was higher in the FEVR group except for the inferior sector (superior, p =0.027; inferior, p =0.88; temporal, p =0.035; nasal, p =0.027). The SE and AL did not differ between the two groups. There were no correlations between the surface and deep layer FAZ area and age, CRT, SE, and AL. The surface, deep FAZ area, and foveal IRT were correlated negatively (surface, r = −0.47, p =0.033; deep layer FAZ area, r = −0.46, p =0.037). Conclusion Eyes with FEVR have a smaller FAZ because the vascular structure in the inner retina remained in the fovea.

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