Self-organized lipid structures (protocells) have been proposed as an intermediate between nonliving material and cellular life. Synthetic production of model protocells can demonstrate the potential processes by which living cells first arose. While we have previously described a giant vesicle (GV)-based model protocell in which amplification of DNA was linked to self-reproduction, the ability of a protocell to recursively self-proliferate for multiple generations has not been demonstrated. Here we show that newborn daughter GVs can be restored to the status of their parental GVs by pH-induced vesicular fusion of daughter GVs with conveyer GVs filled with depleted substrates. We describe a primitive model cell cycle comprising four discrete phases (ingestion, replication, maturity and division), each of which is selectively activated by a specific external stimulus. The production of recursive self-proliferating model protocells represents a step towards eventual production of model protocells that are able to mimic evolution.

We investigate the dynamical coupling between the motion and the deformation of a single selfpropelled domain based on two different model systems in two dimensions. One is represented by the set of ordinary differential equations for the center of gravity and two tensor variables characterizing deformations. The other is an active cell model which has an internal mechanism of motility and is represented by the partial differential equation for deformations. Numerical simulations show a rich variety of dynamics, some of which are common to the two model systems. The origin of the similarity and the difference is discussed.

The FOREST Unbiased Galactic plane Imaging survey with the Nobeyama 45-m telescope (FUGIN) project is one of the legacy projects using the new multi-beam FOREST receiver installed on the Nobeyama 45-m telescope. This project aims to investigate the distribution, kinematics, and physical properties of both diffuse and dense molecular gas in the Galaxy at once by observing 12 CO, 13 CO, and C 18 O J = 1 − 0 lines simultaneously. The mapping regions are a part of the 1st quadrant (10• ) of the Galaxy, where spiral arms, bar structure, and the molecular gas ring are included. This survey achieves the highest angular resolution to date (∼20 ′′ ) for the Galactic plane survey in the CO J = 1 − 0 lines, which makes it possible to find dense clumps located farther away than the previous surveys. FUGIN will provide us with an invaluable dataset for investigating the physics of the galactic interstellar medium (ISM), particularly the evolution of interstellar gas covering galactic scale structures to the internal structures of giant molecular clouds, such as small filament/clump/core. We present an overview of the FUGIN project, observation plan, and initial results, which reveal wide-field and detailed structures of molecular clouds, such as entangled filaments that have not been obvious in previous surveys, and large-scale kinematics of molecular gas such as spiral arms.