We report two cases of male breast cancer. Case I, a 69-year-old male (T. U.) with a chief complaint of a walnut-sized firm lump on the left side of the breast (stage H: T2aN1bM0) was hospitalized for surgical treatment, and radical mastectomy was performed. Four years and five months later, he died of cerebral apoplexy. Case II, a 75-year-old male (E. K.), was found to have a hen egg-sized firm tumor on the right side of the breast and had some discomfort after eating. He was diagnosed as having synchronous double cancer, i.e., breast cancer (stage II: T1N1bM0) and gastric cancer (MAC, Borrman III type).Radical mastectomy and total gastrectomy with splenectomy and partial pancreatectomy was performed. Since estrogen receptor and progesterone receptor were recognized in the breast cancer tissue, combined endocrine chemotherapy was performed after surgery. No recurrence and symptoms or signs of gastrointestinal disturbance have been observed up to the time of writing. It was of interest that this patient had three women with breast cancer among his relatives. In the Japanese literature, 354 cases of male breast cancer have been reported up to the present. Male breast cancer accounts for only about 1% of all breast cancers.
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