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SummaryThis study assessed the biochemical status of serum atocopherol (Toe) and lipid in university students (60 males and 51 females) and searched for risk factors of coronary heart disease (CHD). No significant differences were observed between the sexes in total cholesterol (T-C) (170 and 181 mg/ 100 ml for males and females, respectively), low density lipoprotein-cholesterol (LDL-C) (116 and 118 mg/ 100 ml), and phospholipids (PL) (193 and 199 mg/ 100 ml). The levels of high density lipoprotein-cholesterol (HDL-C) were lower in males (54 mg/ 100 ml) than in females (62 mg/ 100 ml, p<0.001) and those of triglyceride (TG) were higher (74 and 59 mg/100 ml for males and females, respectively, p<0.01). There were also no significant differences in HDL-C as a percentage of T-C (32 and 35%) and the LDL-C/HDL-C ratio (2.3 and 2.0). Toe level and the Toc/T-C ratio were significantly lower in males (5.16 ,u g/ml and 3.11 ,u g/mg, respectively) compared with females (6.15 ,u g/ml and 3.46 ,u g/mg, respectively) (p<0.001 for Toe and p < 0.05) for Toc/T-C. A direct relationship was found between the T-C level and LDL-C (r=0.92, p<0.001) and HDL-C (r=0.40, p<0.001). The atherogenic index, the LDL-C/HDL-C ratio, showed a positive correlation with the T-C level (r = 0.43, p<0.001) and a negative correlation with the HDL-C level (r = -0.63, p<0.001). The T-C levels also could be correlated with the levels of Toe (r = 0.37, p<0.001) and inversely correlated with the Toc/T-C ratio (r= -0.41, p<0.001). The Toc/T-C ratio showed an inverse correlation with the LDL-C/HDL-C (r= -0.31, p<0.001). These results reveal that the T-C level affects the vitamin E status and that the Toc/T-C ratio can be used to assess trends in CHD risk factors.

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