Biologic and technical complications are widely reported in the dental literature and often compromise the functional and/or aesthetic features of fixed, implant‐supported prostheses. Managing complications without damaging or destroying a restoration is an obvious advantage of implant‐based dentistry where the option of prosthetic retrievability is almost always available. The technique of cross‐pinning uses a transverse screw to secure a prosthesis to a milled implant abutment, allowing prosthetic retrievability irrespective of dental implant alignment. This study presents guidelines for cross‐pinning implant‐supported prostheses based on resistance form, screw mechanics and natural tooth contours. The technical aspects of cross‐pinning are also discussed using examples from four implant systems.