The development of Nausea and Vomiting in Pregnancy (NVP) is rife, affecting approximately 80% of pregnant females, where only 1% of these might progress to develop a severe form of NVP known as hyperemesis gravidarum [1][2][3] . NVP is commonly seen between the 5 th and the 18 th weeks of gestation, and affect the overall well-being of patients 4 . Importantly, the severity of the NVP varies among pregnants, and consequently, the management will vary as well. Although there are plenty of etiologies and pathophysiological theories underpinning NVP, it is still considered to be an area of controversy 5. The importance of addressing NVP lies behind the possibility of developing dehydration, affecting the pregnancy, affecting the quality of life, productivity, and might lead to depression 6 . Treatment modalities incorporate identifying trigger factors and avoiding them, utilizing pharmacological and complementary agents and supportive therapy 7-9 .Ginger (Zingiber officinale), which is a common ingredient in Asian meals, started gaining momentum as a treatment modality for NVP 10 . Noncompliance to medications and treatment plans is not uncommon among pregnant women which might be gauged by concerns related to fetus health 11 . However, herbal or complementary medicine tends to be more accepted as they are perceived to be a safer option although they might be not 12 . Hence, this systematic review aims at investigating the efficacy of ginger in relieving NVP. Although investigating the safety of this ingredient is imperative, the majority of studies included in this systematic review were conducted for a very short period (e.g. four days), and used different doses and dosage forms, therefore rendered this objective unachievable. AbstractNausea and Vomiting (N/V) are unpalatable manifestations seen commonly during pregnancy, which impinge upon the overall well-being, the productivity and might result in hospitalization. There is growing evidence concerning the efficacy of ginger in alleviating Nausea and Vomiting in Pregnancy (NVP). Therefore, we sought to conduct a systematic review to explore the effectiveness of ginger for NVP. A comprehensive search was conducted in Google Scholar, PubMed, and Science Direct which resulted in identifying five studies. These studies showed that ginger can improve NVP in a statistically significant manner (P< 0.05). Assessing the safety profile of this agent was difficult due to the short duration of intervention, and inconsistency in the dose and dosage form of ginger used. This study helped to glean evidence about the efficacy of ginger in NVP. It also emphasized the need for conducting more studies with a better quality and that are using standardized dose and dosage forms to be able to conduct a meta-analysis.