Objectives:The objective is to know the extent of agreement of clinicians’ perception of nasolabial esthetic compared to that of laypeople (parents).Materials and Methods:This was a prospective study of comparison of clinician's perception of nasolabial esthetics with that of laypeople following surgical repair of UCL. Participants were recruited from the Cleft Clinic of the Lagos University Teaching Hospital, and surgical repair of the cleft was performed under general anesthesia. Surgical evaluation was done through direct clinical evaluation using the modified form of the Christofides’ criteria by laypeople and professionals.Results:A total of 48 cleft participants were enrolled in the study. The evaluation of the lip by both the laypeople and professionals was similar, and there was no difference (0.588) in their rating. However, there was a significant disagreement (P = 0.001) between them in the nose assessment.Conclusion:Neither the solitary opinion of the professionals nor that of the laypeople is satisfactory in the evaluation of facial esthetics; both are equally important, especially in the assessment of nasal esthetics. However, opinion of either the laypeople or the professional might be enough in the evaluation of the lip esthetics.

Background: The number of recurrent tonsillitis and tonsillar hyperplasia requiring tonsillectomies annually is huge. Poor oral hygiene has been linked with the occurrence of these tonsillar diseases. The main objective of the present study is to determine the oral hygiene status of patients treated for tonsillitis and/or tonsillar hyperplasia at our hospital. Methods: This was a prospective case series of participants with tonsillitis or tonsillar hyperplasia at our hospital from 2018 to 2020. Results: A total of 80 participants with tonsillitis/or tonsillar hyperplasia were recruited into the study within August 2016 and March 2017 comprising 49 (61.3%) females and 31 (38.7%) males, with age ranging from 16 to 32 years (18.27 ± 4.21). Conclusions: The present study demonstrated a high proportion of less than optimal oral hygiene status in participants with tonsillitis/or tonsilar hyperplasia. This suggests that there might be an association between oral hygiene and tonsillitis/or tonsilar hyperplasia. Further research is, however, needed to prove this.

Objective: Sickle cell disease (SCD) is a haemoglobinopathy that causes several clinical complications. Unripe Carica papaya has been shown to possess antisickling activity that could reduce these complications. This study aimed to examine the presence of antisickling and sickling-reversal activities of aqueous extracts and ethyl acetate fractions of C. papaya fruit at different stages of ripening. Methods: Unripe, partly ripe, and fully ripe fruits were quantitatively screened for some phytochemicals using standard methods. Blood samples from sickle cell patients were used to investigate antisickling and sickling reversal activities of aqueous extracts and ethyl acetate fractions of the fruits. Data were analysed using one-way ANOVA. The p-value was set at 0.05. Results: Phytochemicals such as alkaloids, saponins, tannins, flavonoids and polyphenols were found in varying concentrations in C. papaya fruit at the different stages of ripening. All extracts and fractions showed antisickling and sickling-reversal activities with the ethyl acetate fraction of partly ripe C. papaya being most effective.  Conclusion: The study showed that C. papaya fruit at different stages of ripening contains antisickling and sickling-reversal activities which may help reduce the associated complications of SCD when consumed by affected individuals.

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