Background Diabetic neuropathy is the primary cause of foot ulcers and amputations in both industrialized and poor countries. In spite of this, most epidemiological research on diabetic neuropathy in Ethiopia have only made an effort to estimate prevalence, and the information underlying the condition’s beginning is not well-established. Therefore, determining the time to diabetic neuropathy and its variables among adult patients with type 2 diabetes mellitus at the Compressive Specialized Hospitals of the Amhara region was the aim of this study. Methods An institutional-based retrospective follow-up study was undertaken among 669 newly recruited adult patients with type 2 diabetes mellitus who were diagnosed between the first of March 2007 and the last day of February 2012. Patients with diabetic neuropathy at the time of the diagnosis for type 2 diabetes mellitus (T2DM), patients without a medical chart, patients with an unknown date of DM diagnosis, and patients with an unknown date of diabetic neuropathy diagnosis were excluded from the study. All newly diagnosed type 2 diabetes mellitus (T2DM) patients aged 18 years and older who were enrolled from 1st March 2007 to 28th February 2012 in selected hospitals were included in this study. Cox proportional hazard model was fitted to determine predictors of time to diabetic neuropathy, and the Kaplan Meier survival curve was used to assess the cumulative survival time. Variables with a p-value < 0.05 were considered to be statistically significance at 95% confidence interval. Results The restricted mean survival time of this study was 179.45 (95% CI: 173.77–185.14) months. The overall incidence rate of diabetic neuropathy was 2.14 cases per 100 persons-years. Being aged > 60 years [AHR = 2.93(95% CI: 1.29–6.66)], having diabetic retinopathy [AHR = 2.76(95% CI: 1.84–4.16)], having anemia [AHR = 3.62 (95% CI: 2.46–5.33)], having hypertension [AHR = 3.22(95% CI: 2.10–4.93)], and baseline fasting blood sugar > 200 mg/dl [AHR = 2.56(95% CI: 1.68–3.92)] were the predictors of diabetic neuropathy. Conclusion The risk of occurrence of diabetic neuropathy among type two diabetes mellitus patients was high in the early period. Age > 60 years, diabetic retinopathy, anemia, baseline fasting blood sugar level > 200 mg/dl, and hypertension were the main predictors of incidence of diabetic neuropathy. Therefore, early detection and appropriate interventions are important for patients with old age, diabetic retinopathy, anemia, hypertension, and FBS > 200mg/dl.
Background: Understanding how people perceive the risk of the coronavirus disease outbreak and its impact on undertaking protective behavior can guide the public health policymakers in taking the required measures to limit the magnitude of this outbreak.Objective: This study aimed to assess the knowledge, risk perceptions, and uptake of preventive measures towards COVID-19 in East Gojjam zone.Methods: A mixed method study in order to obtain in-depth behavioral insights related to COVID-19 pandemic prevention measures was conducted in the four randomly selected Woredas of East Gojjam Zone. A flexible data collection tool adapted from World Health Organization (WHO) for quantitative component, and in-depth interview for qualitative component was used. Binary logistic regression analysis was conducted to analyze quantitative data, and while content analysis was used for qualitative component.Results: In this study, a total of 661 study participants were included. Nearly two-third (65.5%) of respondents is residing in the rural area. Only 59.6% of respondents had better understanding of COVID-19 pandemic. Similarly, less-than one-fifth (14.5%) of individuals had favorable attitude towards COVID-19. This study showed that only one-fifth (20.9%) of study participants had good preventive practices. Respondent’s residing in urban area (AOR: 0.1, 95%CI: 0.08, 0.2), who had age between 35 and 45 (AOR: 0.4, 95%CI: 0.2, 0.8), and having secondary and above education level (AOR: 0.2, 95%CI: 0.1, 0.5) had better awareness towards COVID-19 as compared to its counterparts. Similarly, study participants who had better knowledge ((AOR: 3.0, 95%CI: 1.7, 5.5), and residing in urban area had favorable attitude towards COVID-19. Furthermore, respondents with confirmed comorbidity had good preventive practice towards COVID-19.Conclusion and recommendation: In this study, the level of knowledge, attitude and preventive practice towards COVID-19 is low. Residing in rural area, not having formal education, being housewife were factors significantly associated with the poor level of knowledge, attitude, and preventive practice towards COVID-19. Address peoples living in rural area through health professional to create public awareness towards COVID-19 is recommended.
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