American Diabetes Association (ADA), Diabetes Canada (DC) published updates to the management of Diabetic peripheral neuropathy (DPN) in 2017 and 2018. National Institute of Healthcare and excellence (NICE) also updated their guidelines for management of neuropathic pain in 2018. This article aims to review the topic given those updates and to highlight similarities as well as differences in management. The authors will focus on implications and their clinical application in everyday practice.