Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4-1.5). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0-2 weeks, 3-4 weeks and 5-6 weeks of the diagnosis (odds ratio (95%CI) 4.1 (3.3-4.8), 3.9 (2.6-5.1) and 3.6 (2.0-5.2), respectively). Surgery performed ≥ 7 weeks after SARS-CoV-2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5 (0.9-2.1)). After a ≥ 7 week delay in undertaking surgery following SARS-CoV-2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2-8.7) vs. 2.4% (95%CI 1.4-3.4) vs. 1.3% (95%CI 0.6-2.0), respectively). Where possible, surgery should be delayed for at least 7 weeks following SARS-CoV-2 infection. Patients with ongoing symptoms ≥ 7 weeks from diagnosis may benefit from further delay.
SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 days of surgery. SARS-CoV-2 diagnosis was defined as peri-operative (7 days before to 30 days after surgery); recent (1-6 weeks before surgery); previous (≥7 weeks before surgery); or none. Information on prophylaxis regimens or pre-operative anti-coagulation for baseline comorbidities was not available. Postoperative venous thromboembolism rate was 0.5% (666/123,591) in patients without SARS-CoV-2; 2.2% (50/2317) in patients with peri-operative SARS-CoV-2; 1.6% (15/953) in patients with recent SARS-CoV-2; and 1.0% (11/1148) in patients with previous SARS-CoV-2. After adjustment for confounding factors, patients with peri-operative (adjusted odds ratio 1.5 (95%CI 1.1-2.0)) and recent SARS-CoV-2 (1.9 (95%CI 1.2-3.3)) remained at higher risk of venous thromboembolism, with a borderline finding in previous SARS-CoV-2 (1.7 (95%CI 0.9-3.0)). Overall, venous thromboembolism was independently associated with 30-day mortality ). In patients with SARS-CoV-2, mortality without venous thromboembolism was 7.4% (319/4342) and with venous thromboembolism was 40.8% (31/76). Patients undergoing surgery with peri-operative or recent SARS-CoV-2 appear to be at increased risk of postoperative venous thromboembolism compared with patients with no history of SARS-CoV-2 infection. Optimal venous thromboembolism prophylaxis and treatment are unknown in this cohort of patients, and these data should be interpreted accordingly.
Employability skills are among the important soft skills that should be acquired by employees in the industrial sector today. Unfortunately, Malaysian graduates do face obstacles when looking for employment upon graduation due to the absence of employability skills among them. The main aim of this study is to identify employers' perceptions of the most important employability skills in the manufacturing industry. The study is also aimed to determine the differences between the important employability skills from the perspective of employers based on their gender, their company's size, and types of companies in the manufacturing industry. In this study, a total of 182 employers from the manufacturing industry in Batu Pahat were chosen randomly. Questionnaires were administered to the employers. The data generated were statistically analysed using descriptive and inferential analyses. The analysis shows that employers' perception of the most important employability skills in manufacturing industry is communication skills. The independent variables chosen are gender, company size, and types of manufacturing sector, while the dependent variable is the perceptions of important employability skills in the manufacturing industry. Results show that the perceptions of important employability skills in the manufacturing industry have no significant difference according to employers' gender and type of manufacturing sector, but there is a significant difference for company size. This quantitative study provides key insights that enable future employees to have more understanding of the employment demand in the manufacturing industry nowadays and for employees to develop their employability skills before getting ready to enter the labour market.
Good quality of sleep is an acknowledged source of physical and mental wellbeing, happiness, and vitality. Without enough hours of restorative sleep, the individual will not be able to function, study, develop and interact even near to their true potential at a point of time. University student's lifestyle changes with the new life of studying. Sleep problems and sleep disorders severely impair university students' academic success. To date, there is limited study on the level of sleep quality among university students during the covid-19 lockdown. The purpose of this study was to determine the level of sleep quality among university students between faculty during the Covid-19 lockdown. A total of 417 respondents among Universiti Teknologi MARA (UiTM) Perlis were set up to answer the questionnaire by Pittsburgh Sleep Quality Index (PSQI). Based on the data, there was a significant difference in the level of sleep quality among UiTM Perlis Student (p = 0.001). The mean global score for all students was (6.47 ± 3.105). Faculty of Architecture Planning and Surveying had a higher mean global score (8.95 ± 2.882). Faculty of Sports Science and Recreation had a lower mean global score (3.86 ± 2.014). From the result, Faculty Architecture Planning and Surveying have poor sleep quality while Faculty of Sports Science and Recreation have good sleep quality. In conclusion, the study showed the level of sleep quality among UiTM Perlis students is slightly greater on poor sleep. This might be due to poor sleep habits like having an irregular sleep pattern and psychological issues such as stress.
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