One of the main and acceptable causes of infertility in men is 'varicocele' due to the abnormal enlargement and dilation of the testicular veins (especially the left one), the pathological consequences of which are testicular damage and reduced sperm quality (Jensen et al., 2017). According to the literature background, several mechanisms could account for these pathological consequences including hypoxia, increased testicular temperature, changes in testicular blood flow and venous pressure, stasis, inflammation, decreased gonadotropins and androgens, oxidative stress (OS) and apoptosis.Most of these factors can be related to an increase in testicular temperature, the consequence of which is an increase in oxidative stress that can have detrimental effects on cell and tissue health. Oxidative stress occurs as a result of either increased production of reactive oxygen species (ROS) or reduced antioxidant production capacity