Aim:The aim of the present study was to assess the shade difference between zirconia strengthened lithium silicate ceramic (Celtra Press) VS lithium disilicate glass ceramics (e.max) in reference to the natural tooth optical properties to determine which monolithic material will replicate the exact shade and optical properties of the corresponding natural tooth structure.Materials and Methods: 20 teeth esthetic zone requiring full coverage crown -with their adjacent/contralateral are sound and not severely discolored -were selected to receive a ceramic crown and divided into 2 groups: Group 1: Teeth prepared to receive crowns fabricated from IPS e.max press (Ivoclar Vivadent) Group 2: Teeth prepared to receive crowns fabricated from Celtra Press (Dentsply Sirona). The patient satisfaction values of the two groups was evaluated using Visual Analogue Scale (VAS) of satisfied or unsatisfied documented in a chart. Color difference in reference to the natural tooth was evaluated by 3 experienced evaluators using modified United States public health service (USPHS) criteria as Alpha(excellent), Bravo (acceptable), Charlie(acceptable but alterations required) and Delta(unacceptable). The color difference ΔE (perceptibility threshold) was measured using intraoral spectrophotometer and evaluated for each group.Results: Regarding patient satisfaction, there was no statistically significant difference between (Group I) and (Group II) where (p=1) as both groups showed (100%) Alpha satisfied. Concerning shade matching, there was no statistically significant difference between (Group I) and (Group II) where (p=1) as both groups showed (100%) Alpha. Conclusions:Within the limitations of this clinical study, Celtra Press and Emax press materials when used for full coverage restorations resulted in excellent patient satisfaction and color matching results. This dictates that both materials have clinical acceptable shade matching and patient satisfaction.