The Kleine-Levin syndrome is a rare pathology characterized by recurrent episodes of hypersomnia associated with behavioral and cognitive disorders with, among others, hyperphagia and hypersexuality. The disease mainly affects young males. A few studies mention cases that occurred in Africa, especially in Côte d'Ivoire. In this paper, we report the very first two cases observed in the Neurology Department of the University Hospital of Cocody. The diagnosis was clinical, based on the recurrence of hypersomnia, cognitive and behavioral disorders during the periods of hypersomnia, and the return of patients to normal state between episodes. This diagnosis was delayed due to failure to understand the pathology, thereby leading patients to wandering. In fact, the two patients were consulted, respectively, 3 years and 6 years after the hypersomnia began. The objective was to report the very first cases observed in the Neurology Department of the University Hospital of Cocody, Côte d'Ivoire.

TheKleine-Levin syndrome (KLS)is classied among rare diseases[1, 2]. It belongs to the central hypersomnias said to be recurrent and dened according to the International Classication of Sleepiness Disorders, 3rd version (ICSD-3), revised in 2014. For the ICSD-3, the Kleine-Levin syndrome is a disorder characterized by recurrent episodes of hypersomnia andhyperphagia (rapidconsumptionof a large amountoffood),usually with onset in early adolescence inmales but occasionally in laterlife and in women.Amonosymptomatic form of the disorder with hypersomnia only can occur with- out binge eating or hypersexuality [1]. Usually affecting adolescent males, episodes normally last up to a few weeks and terminate with total and spontaneous recovery. Possibly rst reported by Brierre de Bosmont in 1862, the condition however received its name from Willi Kleinewho,in1925,reporteda seriesof casesofperiodichypersomnia and also Max Levin who described a case of periodic hypersomnia and excessive appetite in1930[2].The exactprevalence remainsunknown.But it seems very rare: around one to two cases per million. All cases are not published. A review of the inter- national literature of language between 1962and2004,byArnulf et al.[2], estimatedthenumberofpublishedcases at186.Accordingtotheseauthors,theannualincidencewas2.7in1970,3.5 in 1980, and 5.8 in the 1990s. For these authors, this growth would rather correspond to the extension ofthe globalscientic communication than an actual increase in the prevalence of the syndrome. Patients were described aroundtheworld,includingAsiaandAfrica,withcuriouslyone-sixthofthe world's cases described in Israel [1, 2]. Its etiology remains unknown. The genetic trail was discussed in the presence of familial cases [1, 2]. The diseasemainlyaffectsyoungmales[1,2].Itsdiagnosisisclinical[1,3,4].