The interdependence among eating behaviour (EB), physical activity (PA) and sedentary time (ST) suggests simultaneously identifying homogeneous profiles and describing their changes. This study aimed to 1) identify cross-sectional lifestyle behaviour profiles and their 2-year changes among French school-aged adolescents and, 2) identify factors associated with these profiles and changes. Longitudinal data from adolescents who participated in the PRomotion de l’ALIMentation et de l’Activité Physique trial were used. PA and ST were assessed with the International Physical Activity Questionnaire and EB with a food frequency questionnaire. Profiles at baseline and their changes were identified by latent transition analysis. Multinomial logistic regression models were used to identify factors associated with profiles and their changes. Among 2390 adolescents included (14-18 years), five baseline profiles that differed mainly in EB were identified: “healthy diet and high PA (7.9%)”, “big eater and moderate to high PA (23.8%)”, “healthy diet and low PA (31.2%)”, “restrictive diet and moderate PA (20.6%)”, “sugar products, nibbling and moderate PA (16.5%)”. Young adolescents, those who were overweight or obese and socially advantaged were more in the “healthy diet and low PA” than others. Boys, older and socially less advantaged adolescents exhibited more “unfavourable” than “mixed” changes, while adolescents with overweight or obesity had less “unfavourable” than “mixed” changes. In conclusion, adolescents were twice the number in the least than the most favourable profile. Findings highlighted the importance of EB among adolescents and suggest taking adolescents’ sociodemographic and weight characteristics into account in interventions aimed at acting on adolescents’ behaviours.

Introduction: Polycystic Ovarian Syndrome (PCOS), also known as Stein Leventhal Syndrome, is one of the common endocrine diseases affecting women of childbearing age and the leading cause of anovulatory infertility worldwide. The aim of this study was to describe the clinical, paraclinical and therapeutic aspects of PCOS at the University Clinic of Obstetrics and Gynaecology of the National Hospital and University Centre Hubert Koutoukou MAGA of Cotonou (CNHU). Patients and Method: The study was doing in the University Clinic of Gynecology and Obstetrics of the CNHU-HKM. This was a descriptive and analytical longitudinal study with retrospective and prospective data collection over a period of 7 years from January 2015 to December 2021. It focused on women of childbearing age seen in gynecological consultation. Results: The frequency of PCOS was 2.53%. The mean age of the patients was 27.28 ± 6.55 years. They were educated for the most part with a university level in 43.8% of cases. Obstetrically they were nulligest (45.63%) and nulliparous in 60% of cases. The history of spontaneous miscarriages was found in 61.11%. The main reasons for consultation were menstrual disorders (51%) followed by the desire for pregnancy (40.6%). Clinically, obesity (30%), overweight (33.1%), high blood pressure (20.63%), hirsutism (24%) and acne (27%) were noted. All the women had micropolycystic ovaries in ultrasound. Testosterone was elevated in 61% of cases. Phenotype D was found in 45.63% of patients. All these patients were put under lifestyle and dietary measures, Metformin (13.80%) and estrogen-progestogen (18.80%). The outcome of the treatment was assessed by cycle regularity, regression of hirsutism, weight loss, fertility and fertility. The cycle was normalised in most cases with notable regression of physical signs of hyperandro-

Introduction: The pathologies associated with excessive weight gain during pregnancy are numerous and frequent. They are the cause of significant maternal and perinatal morbidity and mortality and thus pose a real public health problem. Patients and method: The main objective of our work was to study the influence of excessive weight gain on maternal and perinatal morbidity and mortality in a university hospital in Cotonou. Study method:The study took place at the CUGO. This was a descriptive and analytical study with retrospective data collection over a period of 10 years from January 1, 2012 to December 31, 2021. The analysis focused on the description of pregnant women and the search for factors associated with an excessive weight gain during pregnancy and which influence maternal and perinatal prognosis. The different odds ratios and their confidence intervals were calculated. The significance level was 5%. Results: A total of 690 pregnant women were included and divided into four sub-populations according to their pre-gestational or first trimester BMI: 05.94% underweight pregnant women, 41.74% normal BMI pregnant women, 28.55% of overweight pregnant women and 23.77% obese pregnant women. The average age of pregnant women was 30.41 years ± 5.40 years. They were civil servants (35.80%) and resided in Cotonou in 93.91% of cases. Pregnant women had a history of hypertension in nearly 3% of cases. Pregnancy hypertension (07.97%) was the main pathology associated with pregnancy in our study. Weight gain was excessive in overweight pregnant women and obese pregnant women in the same proportion 41.12%. The average weight gain was 9.42 kg for underweight pregnant women, 8.35 kg for pregnant women with a normal BMI, 8.46 kg for overweight pregnant women and 7.45 kg for obese pregnant women. Pregnant women who had gained ex-

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Background Nutritional behaviours such as diet, physical activity (PA) and sedentary behaviour (SB) are interdependent and are likely to change in different way during a public health intervention. This study aimed to 1) identify cross-sectional nutritional profiles and their 2-year longitudinal transition among French school-aged adolescents, 2) identify factors associated with these profiles and transition. Methods Adolescents from the 2-year school-based PRALIMAP (PRomotion de l'ALIMentation et de l'Activité Physique) intervention were included. Nutritional behaviours (diet, PA and SB) were assessed by self-administered questionnaire at the beginning (T0) and end (T2) of the study. Nutritional profiles were identified at T0 using latent class analysis, and their transition from T0 to T2 using latent transition analysis. Logistic regression models were computed to identify associated factors such as sex, weight status, age, socioeconomic status and a PRALIMAP intervention. Results Among the 2390 adolescents included (mean ± SD age=15.1 ± 0.6 years), 5 nutritional profiles were evidenced at T0 and labelled as ‘healthy'(12.2%), ‘excessive diet' (16.0%), ‘physically inactive' (26.1%), ‘restrictive diet' (23.5%), and ‘unhealthy' (22.2%). Compared to ‘physically inactive' profile, adolescents from the ‘healthy' ones were less likely to be girls (OR = 0.21; p>.0001), and socially advantaged (OR = 0.87; p=.0002). ‘Unhealthy' profile adolescents were less likely to be overweight/obese (OR = 0.48; p>.0001) and more likely to be older (OR = 3.67; p>.0001). At T2, proportion of adolescents increased in ‘healthy' (+4.6%), ‘unhealthy' (+2.8%) profiles, and decreased in ‘excessive diet' (-1.2%), ‘physically inactive' (-3.2%), ‘restrictive diet' (-3.03%) profiles. Compared to the control group, adolescents from the intervention group were more likely to remain in ‘healthy' (OR = 1.3), and to switch from ‘excessive eater' (OR = 1.1) and ‘physically inactive' (OR = 2.6) to ‘healthy'. Sustainability of ‘healthy' profile increased with socioeconomic status. Conclusions The results of this study confirm the variety of behavioural profiles in nutrition with significant social differences. It also demonstrated the effectiveness of the intervention in changing behaviours favourably. Public health focusing on nutritional changes may be more effective it taking in to account the social status of adolescents.