The knowledge discovery has been widely applied to mine significant knowledge from medical data. Nevertheless, previous studies have produced large numbers of imprecise patterns. To reduce the number of imprecise patterns, we need an approach that can discover interesting patterns that connote causality between antecedent and consequence in a pattern. In this paper, we propose association rule mining method that can discover interesting patterns that include medical knowledge in Korean acute myocardial infarction registry that consists of 1,247 young adults collected by 51 participating hospitals since 2005. Proposed method can remove imprecise patterns and discover target patterns that include associations between blood factors and disease history. The association that blood factors affect to disease history is defined as target pattern. In our experiments, the interestingness of a target pattern is evaluated in terms of statistical measures such as lift, leverage, and conviction. We discover medical knowledge that glucose, smoking, triglyceride total cholesterol, and creatinine are associated with diabetes and hypertension in Korean young adults with acute myocardial infarction.

Coronary heart disease is being identified as the largest single cause of death along the world. The aim of a cardiac clinical information system is to achieve the best possible diagnosis of cardiac arrhythmias by electronic data processing. Cardiac information system that is designed to offer remote monitoring of patient who needed continues follow up is demanding. However, intra- and interpatient electrocardiogram (ECG) morphological descriptors are varying through the time as well as the computational limits pose significant challenges for practical implementations. The former requires that the classification model be adjusted continuously, and the latter requires a reduction in the number and types of ECG features, and thus, the computational burden, necessary to classify different arrhythmias. We propose the use of adaptive learning to automatically train the classifier on up-to-date ECG data, and employ adaptive feature selection to define unique feature subsets pertinent to different types of arrhythmia. Experimental results show that this hybrid technique outperforms conventional approaches and is, therefore, a promising new intelligent diagnostic tool.

No abstract

No abstract

SUMMARYA reliable detection of atrial fibrillation (AF) in Electrocardiogram (ECG) monitoring systems is significant for early treatment and health risk reduction. Various ECG mining and analysis studies have addressed a wide variety of clinical and technical issues. However, there is still room for improvement mostly in two areas. First, the morphological descriptors not only between different patients or patient clusters but also within the same patient are potentially changing. As a result, the model constructed using an old training data no longer needs to be adjusted in order to identify new concepts. Second, the number and types of ECG parameters necessary for detecting AF arrhythmia with high quality encounter a massive number of challenges in relation to computational effort and time consumption. We proposed a mixture technique that caters to these limitations. It includes an active learning method in conjunction with an ECG parameter customization technique to achieve a better AF arrhythmia detection in real-time applications. The performance of our proposed technique showed a sensitivity of 95.2%, a specificity of 99.6%, and an overall accuracy of 99.2%.