No abstract

Nowadays bronchial asthma and increased body weight represent major problems in children. Asthmatic attacks in obese patients are not well controlled using the conventional treatment regimens. Asthma has been associated with increased systemic and exhaled levels of hydrogen peroxide and thiobarbituric acid-reactive products in expired breath condensate of asthmatic patients. Thiobarbituric acid reactive substances formed from peroxidation of lipids. The aim of the Study is to show the action of Thiobarbituric acid reactive substances activity in asthma among overweight children suffering from asthma and to detect the connection between this biomarker and the etiology, degree of severity among children with bronchial hypereactivity. The study is cross-sectional study, was conducted on Egyptian children on regular follow up at the outpatients pediatric allergy clinic in Bab El-shariea university Hospital, Al-Azhar University. The study group included 96 child divided into 4 groups. Group A which included overweight children with (mild persistent asthma). Group B which included non-overweight children with (mild persistent asthma).Group C which included overweight non-asthmatics children and Group D The control group (non-overweight non-asthmatics). The results showed significant increase in the Thiobarbituric acid reactive substances level in Overweight asthmatic patients in relation to non-overweight patients with asthma. We found that they can distinguish asthma controlled patients from non-asthma controlled patients. This study showed high level of oxidative stress with high asthma severity as measured by Thiobarbituric acid reactive substances. These substances were good markers of relation between bronchial hyper activity and oxidative stress which became high with asthma severity.

Restoration after endodontic treatment is as important as root canal therapy for clinical success. Evolution of adhesive dentistry strongly aided in the conservation of tooth structure and reinforcement of the restored teeth. Self-etch adhesives has evolved aiming to reduce the technique sensitivity and simplifying the steps needed for bonding (one or two steps). Dual cured self-etch adhesives were also introduced to be more chemically compatible with the resin composite restorations. Bulk-fill resin composites has also achieved great popularity due to the ease of application and being more time saving. These materials made the direct restoration of endodontically treated teeth more conservative, time saving and reliable. This research was performed to assess the clinical success of the restorations of the endodontically treated molars with remaining three walls restored using self-etch adhesives and bulk fill resin composite in comparison to conventional nanohybrid resin composite at a time intervals of 1week (baseline) , 3 ,6 and 12 months. In a randomized clinical trial, 40 patients with endodontically treated molars with remaining three walls received a restorative intervention with either (Xtra-Fil) bulk fill resin composite or (Grandio) nano hybrid resin composite applied in incremental technique.

No abstract