Purpose: The purpose of this study is to investigate the effectiveness of Hyperpolarized Light on lower limb cellulitis with lymphatic disorders. Methods: Thirty patients with lower limb cellulitis with lymphatic disorders participated in the study and were divided randomly into two equal groups. Group (A) received Hyperpolarized Light and Traditional Skin Care; Group (B) received Traditional skin care only. Both groups were assessed before and after treatment by using ALT 70 diagnostic model. Results: Statistical tests for normality revealed that most of variables were non-normally distributed. So, nonparametric tests were used for within group differences (Wilcoxon Signed Rank Test) and between groups differences (Mann-Whitney U Test). Statistical test used revealed that there was statistically significant difference between groups with significant reduction in ALT posttest in favor of study group A or study group (P-value<0.001). Statistical tests used revealed that there were no statistically significant differences between two groups (Study and control) in any variable of demographic and clinical data patients (P- value >0.05). So, patients participated in the two groups were homogenous.

Background Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side effects of antineoplastic agents, with a prevalence of 19 to 85%. In terms of clinical manifestations, CIPN is primarily a sensory neuropathy with motor and autonomic alterations of varying intensity and duration. CIPN consider as major problem for both cancer patients and survivors, as well as for their healthcare providers, possibly increasing the risk of falling. Objective: To evaluate the efficacy of game-like interactive exercise versus visual feedback training on the risk of falling and sensory integration in patients with chemotherapy-induced peripheral neuropathy after mastectomy. Methods: In this randomized comparative study, 30 female patients diagnosed with chemotherapy-induced peripheral neuropathy after mastectomy were randomly allocated into two equal groups; group (A) underwent game-like interactive exercise using the Biodex Balance System (BBS), while group (B) underwent a visual feedback training program using BBS. The treatment was applied for three sessions per week for four consecutive weeks. All subjects in both groups were assessed using the fall risk index and sensory integration test (sway index) in four sensory conditions at baseline and at the end of the study for both groups.