Background: Valproate is a broad spectrum anti-convulsant drug used to control all types of seizures. Inspite of its effectiveness in the management of epilepsy, valproate induces skeletal and neurological malformations when used by the pregnant women. Folic acid is an essential nutrient required for normal cell development and metabolism. We aimed in our work to evaluate the possible protective role of folic acid against the valproate-induced skeletal and neurological congenital malformations. Methods: This experiment was done in the animal house in the Faculty of Medicine, Ain Shams University using ninety adult mice "Sixty females and thirty males''. The histopathological procedures were done in Histology Department, Faculty of Medicine, Al-Azhar University. Results: Valpeoate produced numerous neurological and skeletal congenital anomalies in mice fetuses when given to the pregnant females. The concomitant administration of folic acid ameliorated the teratogenic effects of valproate. Conclusions: Folic acid is effective in prevention of the neurological and skeletal congenital malformations induced by valproate.

Artificial intelligence (AI) has recently increased in its use.2017 represents the start of this new era for the hearing aid industry, artificial intelligence H.A. and it offers great promise in overcoming hearing challenges. In our opinion, artificial intelligence is the next revolution in hearing aids after the application of digital signal processing and wireless technology. With the use of artificial intelligence (AI), it will be easier for hearing-impaired persons to understand speech more clearly, especially in different environmental situations. Artificial intelligence (AI), usually synonymous with machine learning, is the ability of computers to simulate human intelligence in problem-solving, logical reasoning, and managing complicated problems. Without being programmed, artificial intelligence can automatically learn from experience. So that it can recognize the wearer's listening environment and then adjust according to the acoustics of each environment. It offers an average 50% reduction in noisy environments, greatly decreasing listening eff ort, and improving speech clarity. So, it provides significant improvement in speech intelligibility in noisy environments.

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